(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-vinylphenyl)propanoic acid

Base Information

Chemical Name:(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-vinylphenyl)propanoic acid
CAS No.:169158-03-6
Molecular Formula:C₁₆H₂₁NO₄
Molecular Weight:291.347
Hs Code.:
DSSTox Substance ID:DTXSID901193370
Mol file:169158-03-6.mol

Synonyms:169158-03-6;(S)-2-((tert-Butoxycarbonyl)amino)-3-(4-vinylphenyl)propanoic acid;(2S)-3-(4-ethenylphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic Acid;(2S)-2-[(TERT-BUTOXY)CARBONYLAMINO]-3-(4-VINYLPHENYL)PROPANOIC ACID;(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-ethenylphenyl)propanoic acid;SCHEMBL18262517;DTXSID901193370;Y13700;N-[(1,1-Dimethylethoxy)carbonyl]-4-ethenyl-L-phenylalanine

Suppliers and Price of (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-vinylphenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-vinylphenyl)propanoic acid

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:291.14705815
Heavy Atom Count:21
Complexity:378

Purity/Quality:: ≥99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)C=C)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CC=C(C=C1)C=C)C(=O)O

Technology Process of (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-vinylphenyl)propanoic acid

There total 5 articles about (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-vinylphenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 169158-02-5
ethyl (2S)-2-[(tert-butoxycarbonyl)amino]-3-(4-vinylphenyl)propanoate

: 169158-03-6
(2S)-2-[(tert-butoxycarbonyl)amino]-3-(4-vinylphenyl)propanoic acid

Guidance literature:: With lithium hydroxide; In methanol; water; at 20 ℃; for 0.333333h;
DOI:10.1248/cpb.49.258

Reference yield: 88.0%

: 103882-09-3,62129-44-6
N-Boc-4-I-Phe-OH

: potassium vinyltrifluoroborate

: 169158-03-6
(2S)-2-[(tert-butoxycarbonyl)amino]-3-(4-vinylphenyl)propanoic acid

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In water; isopropyl alcohol; at 80 ℃; for 1h;
DOI:10.1021/acs.orglett.9b02894

Reference yield:

: potassium vinyltrifluoroborate

: 62129-39-9,79561-82-3
4-bromo-N-{[(1,1-dimethylethyl)oxy]carbonyl}-L-phenylalanine

: 169158-03-6
(2S)-2-[(tert-butoxycarbonyl)amino]-3-(4-vinylphenyl)propanoic acid

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In water; isopropyl alcohol; at 80 ℃; for 24h; Sealed tube;
DOI:10.1002/cctc.201500190