3-Methyl-1-isoquinolinecarbonitrile

Base Information

Chemical Name:3-Methyl-1-isoquinolinecarbonitrile
CAS No.:22381-52-8
Molecular Formula:C₁₁H₈N₂
Molecular Weight:168.198
Hs Code.:2933499090
Mol file:22381-52-8.mol

Synonyms:3-Methyl-1-isoquinolinecarbonitrile;3-Methylisoquinaldonitrile;3-methylisoquinoline-1-carbonitrile

Suppliers and Price of 3-Methyl-1-isoquinolinecarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
3-methyl-1-Isoquinolinecarbonitrile 97.00%
1G
$ 3120.00

Total 3 raw suppliers

Chemical Property of 3-Methyl-1-isoquinolinecarbonitrile

Chemical Property:

PSA：36.68000
LogP:2.41488

Purity/Quality:

99% ^*data from raw suppliers

3-methyl-1-Isoquinolinecarbonitrile 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Methyl-1-isoquinolinecarbonitrile

There total 4 articles about 3-Methyl-1-isoquinolinecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 14548-00-6
3-methylisoquinoline N-oxide

: 7677-24-9
trimethylsilyl cyanide

: 22381-52-8
3-methylisoquinoline-1-carbonitrile

Guidance literature:: With triethylamine; In acetonitrile; for 144h; Heating;
DOI:10.1039/a804340j

Reference yield:

: 3340-64-5
3-methyl-2-(phenylsulfonyl)-1,2-dihydroisoquinoline-1-carbonitrile

: 22381-52-8
3-methylisoquinoline-1-carbonitrile

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm301796k

Reference yield:

: 1125-80-0
3-methylisoquinoline

: 22381-52-8
3-methylisoquinoline-1-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / H₂O₂ / acetic acid; H₂O / 72 h / 70 °C

2: 78 percent / Et₃N / acetonitrile / 144 h / Heating

With dihydrogen peroxide; triethylamine; In water; acetic acid; acetonitrile;
DOI:10.1039/a804340j