2-broMo-4-cyclopropylpyridine

Base Information

• Chemical Name: 2-broMo-4-cyclopropylpyridine
• CAS No.: 1086381-39-6
• Molecular Formula: C₈H₈BrN
• Molecular Weight: 198.062
• Mol file: 1086381-39-6.mol

Synonyms:2-broMo-4-cyclopropylpyridine

Chemical Property of 2-broMo-4-cyclopropylpyridine

Chemical Property:

• PSA: 12.89000
• LogP: 2.72150

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-4-cyclopropylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-broMo-4-cyclopropylpyridine

There total 3 articles about 2-broMo-4-cyclopropylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-amino-5-cyclopropylpyridine (893738-68-6) → 2-bromo-4-cyclopropylpyridine (1086381-39-6)

Guidance literature:

With bromine; sodium hydrogencarbonate; sodium nitrite;

Reference yield:

5-bromo-2-pyridylamine (1072-97-5) → 2-bromo-4-cyclopropylpyridine (1086381-39-6)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium diacetate

2: sodium hydrogencarbonate; sodium nitrite; bromine

With bromine; palladium diacetate; sodium hydrogencarbonate; sodium nitrite;

Reference yield:

2-amino-4-bromopyridine (84249-14-9) → 2-bromo-4-cyclopropylpyridine (1086381-39-6)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium diacetate

2: sodium hydrogencarbonate; sodium nitrite; bromine

With bromine; palladium diacetate; sodium hydrogencarbonate; sodium nitrite;

upstream raw materials:

2-amino-4-bromopyridine

5-bromo-2-pyridylamine

2-amino-5-cyclopropylpyridine

Refernces