1-HYDROXY-2,2,4,5,5-PENTAMETHYL-3-IMIDAZOLINE

Base Information

• Chemical Name: 1-HYDROXY-2,2,4,5,5-PENTAMETHYL-3-IMIDAZOLINE
• CAS No.: 39753-73-6
• Molecular Formula: C8H16N2O
• Molecular Weight: 156.228
• Mol file: 39753-73-6.mol

Synonyms:1-hydroxy-2,2,4,5,5-pentamethyl-2,5-dihydro-1H-imidazole;1-Hydroxy-2,2,4,5,5-pentamethyl-imidazolin;1-Hydroxy-2,2,4,5,5-pentamethyl-3-imidazolin;2,2,4,5,5-Pentamethyl-2,5-dihydro-1H-imidazol-1-ol;2,2,4,5,5-pentamethyl-2,5-dihydro-imidazol-1-ol;1-Hydroxy-2,2,4,5,5-pentamethyl-3-imidazoline;1h-imidazole,2,5-dihydro-1-hydroxy-2,2,4,5,5-pentamethyl;

Chemical Property of 1-HYDROXY-2,2,4,5,5-PENTAMETHYL-3-IMIDAZOLINE

Chemical Property:

• Vapor Pressure: 0.0642mmHg at 25°C
• Melting Point: 126-130oC
• Refractive Index: 1.4535 (estimate)
• Boiling Point: 213.4°Cat760mmHg
• Flash Point: 82.9°C
• PSA: 35.83000
• Density: 1.02g/cm³
• LogP: 1.04030
• Storage Temp.: 0-6°C

Purity/Quality:

98%Min ^*data from raw suppliers

2,2,4,5,5-pentamethyl-2,5-dihydro-1H-imidazol-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-HYDROXY-2,2,4,5,5-PENTAMETHYL-3-IMIDAZOLINE

There total 8 articles about 1-HYDROXY-2,2,4,5,5-PENTAMETHYL-3-IMIDAZOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

→ 1-hydroxy-2,2,4,5,5-pentamethyl-3-imidazoline (39753-73-6)

Guidance literature:

Reference yield: 20.0%

2,2,4,5,5-pentamethyl-2,5-dihydro-1H-imidazol-1-yloxy (39753-74-7) + methylhydrazine hemisulfate (302-15-8,5118-34-3) → 2,2,4,5,5-pentamethyl-1-methoxy-3-imidazoline (88571-39-5) + 1-hydroxy-2,2,4,5,5-pentamethyl-3-imidazoline (39753-73-6)

Guidance literature:

With triethylamine; In methanol; for 20h;

DOI:10.1007/BF00955785

Reference yield:

2,2,4,5,5-pentamethyl-3-imidazolin-3-oxide-1-oxyl (18796-04-8) → 1-hydroxy-2,2,4,5,5-pentamethyl-3-imidazoline (39753-73-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 9 percent / N₂H₄*H₂O / ethanol / 1 h / 20 °C

With hydrazine hydrate; In ethanol;

DOI:10.1007/BF00956162

upstream raw materials:

2,2,4,5,5-pentamethyl-2,5-dihydro-1H-imidazol-1-yloxy

methylhydrazine hemisulfate

diphenyl hydrazine

N-(1,1-Dimethyl-2-oxopropyl)hydroxylamine hydrochloride

Downstream raw materials:

1-(benzyloxy)-2,2,4,5,5-pentamethyl-2,5-dihydro-1H-imidazole

3,4-diamino-2-bromo-4-methyl-1-phenyl-2-pentene-1-thione

4-phenylethynyl-2,2,5,5-tetramethyl-3-imidazoline-1-oxyl

1-hydroxy-4-pentafluorophenylmethyl-2,2,5,5-tetramethyl-3-imidazoline