methyl 4-(acetyloxy)-8-iodo-5,7-dimethoxynaphthalene-2-carboxylate

Base Information

• Chemical Name: methyl 4-(acetyloxy)-8-iodo-5,7-dimethoxynaphthalene-2-carboxylate
• CAS No.: 78395-62-7
• Molecular Formula: C₁₆H₁₅IO₆
• Molecular Weight: 430.196
• Mol file: 78395-62-7.mol

Synonyms:2-Naphthalenecarboxylic acid, 4-(acetyloxy)-8-iodo-5,7-diMethoxy-, Methyl ester

Chemical Property of methyl 4-(acetyloxy)-8-iodo-5,7-dimethoxynaphthalene-2-carboxylate

Chemical Property:

• Vapor Pressure: 4.09E-11mmHg at 25°C
• Boiling Point: 525°C at 760 mmHg
• Flash Point: 271.3°C
• Density: 1.598g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 4-(acetyloxy)-8-iodo-5,7-dimethoxynaphthalene-2-carboxylate

There total 1 articles about methyl 4-(acetyloxy)-8-iodo-5,7-dimethoxynaphthalene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methyl 4-acetoxy-5,7-dimethoxynaphthalene-2-carboxylate (77729-56-7) → methyl 4-acetoxy-8-iodo-5,7-dimethoxy-2-naphthoate (78395-62-7)

Guidance literature:

With mercury(II) diacetate; iodine; In acetic acid;

Reference yield: 92.0%

methyl 4-acetoxy-8-iodo-5,7-dimethoxy-2-naphthoate (78395-62-7) → methyl 4-hydroxy-8-iodo-5,7-dimethoxy-2-naphthoate (78395-63-8)

Guidance literature:

With sodium; In methanol; for 0.25h; Heating;

Reference yield:

methyl 4-acetoxy-8-iodo-5,7-dimethoxy-2-naphthoate (78395-62-7) → methyl 4-hydroxy-5,7-dimethoxy-2-naphthoate (78395-68-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / Na / methanol / 0.25 h / Heating

2: 20 percent / solid / 0.1 h / 120 °C

With sodium; In methanol;

upstream raw materials:

methyl 4-acetoxy-5,7-dimethoxynaphthalene-2-carboxylate

Downstream raw materials:

methyl 4-hydroxy-8-iodo-5,7-dimethoxy-2-naphthoate

methyl 4-hydroxy-5,7-dimethoxy-2-naphthoate