(3-Oxo-3,4-dihydro-2H-benzo[b]-[1,4]oxazin-6-yl)boronic acid

Base Information

• Chemical Name: (3-Oxo-3,4-dihydro-2H-benzo[b]-[1,4]oxazin-6-yl)boronic acid
• CAS No.: 1246765-28-5
• Molecular Formula: C₈H₈BNO₄
• Molecular Weight: 192.967
• Hs Code.: 2934999090
• Mol file: 1246765-28-5.mol

Synonyms:(3-Oxo-3,4-dihydro-2H-benzo[b]-[1,4]oxazin-6-yl)boronic acid

Chemical Property of (3-Oxo-3,4-dihydro-2H-benzo[b]-[1,4]oxazin-6-yl)boronic acid

Chemical Property:

• PKA: 8.06±0.20(Predicted)
• PSA: 78.79000
• Density: 1.46±0.1 g/cm3(Predicted)
• LogP: -1.16470
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(3-Hydroxy-2H-1,4-benzoxazin-6-yl)boronicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-Oxo-3,4-dihydro-2H-benzo[b]-[1,4]oxazin-6-yl)boronic acid

There total 2 articles about (3-Oxo-3,4-dihydro-2H-benzo[b]-[1,4]oxazin-6-yl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

6-bromo-3,4-dihydro-2H-1,4-benzoxazin-3-one (24036-52-0) + tetrahydroxydiboron (13675-18-8) → (3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)boronic acid (1246765-28-5)

Guidance literature:

With nickel(II) chloride hexahydrate; N-ethyl-N,N-diisopropylamine; CyJohnPhos; In methanol; at 25 ℃; for 23h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.joc.0c00929

Reference yield: 66.0%

6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one (943994-02-3) → (3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)boronic acid (1246765-28-5)

Guidance literature:

With hydrogenchloride; water; In acetonitrile; at 20 ℃; for 16h;

upstream raw materials:

6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one

6-bromo-3,4-dihydro-2H-1,4-benzoxazin-3-one

tetrahydroxydiboron

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1246765-28-5 (3-Oxo-3,4-dihydro-2H-benzo[b]-[1,4]oxazin-6-yl)boronic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send