3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-5-(trifluoromethyl)aniline

Base Information

Chemical Name:3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-5-(trifluoromethyl)aniline
CAS No.:510771-54-7
Molecular Formula:C13H17BF3NO2
Molecular Weight:287.09
Hs Code.:2934999090
European Community (EC) Number:873-106-5
DSSTox Substance ID:DTXSID30682237
Wikidata:Q82606544
Mol file:510771-54-7.mol

Synonyms:510771-54-7;3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-5-(TRIFLUOROMETHYL)ANILINE;3-AMINO-5-TRIFLUOROMETHYLPHENYLBORONIC ACID, PINACOL ESTER;3-Amino-5-trifluoromethylphenylboronic acid pinacol ester;SCHEMBL6791563;DTXSID30682237;MFCD16996234;AKOS022184108;MB20260;AS-55353;CS-0175351;EN300-7372475;Z2049755165;3-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-5-(TRIFLUOROMETHYL)ANILINE

Suppliers and Price of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-5-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Amino-5-trifluoromethylphenylboronicacid,pinacolester
100mg
$ 75.00

Crysdot
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)aniline 95+%
1g
$ 371.00

Crysdot
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)aniline 95+%
5g
$ 1240.00

Biosynth Carbosynth
3-Amino-5-trifluoromethylphenylboronic acid, pinacol ester
1 g
$ 550.00

Biosynth Carbosynth
3-Amino-5-trifluoromethylphenylboronic acid, pinacol ester
50 mg
$ 70.00

Biosynth Carbosynth
3-Amino-5-trifluoromethylphenylboronic acid, pinacol ester
500 mg
$ 340.00

Biosynth Carbosynth
3-Amino-5-trifluoromethylphenylboronic acid, pinacol ester
250 mg
$ 200.00

Biosynth Carbosynth
3-Amino-5-trifluoromethylphenylboronic acid, pinacol ester
100 mg
$ 110.00

AK Scientific
3-Amino-5-trifluoromethylphenylboronicacidpinacolester
5g
$ 1384.00

Total 6 raw suppliers

Chemical Property of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-5-(trifluoromethyl)aniline

Chemical Property:

Boiling Point:144-146 °C(Press: 0.7 Torr)
PKA:3.36±0.11(Predicted)
PSA：44.48000
Density:1.19±0.1 g/cm3(Predicted)
LogP:3.16800
Storage Temp.:Refrigerated.
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:287.1304434
Heavy Atom Count:20
Complexity:357

Purity/Quality:

95% ^*data from raw suppliers

3-Amino-5-trifluoromethylphenylboronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CC(=CC(=C2)N)C(F)(F)F

Technology Process of 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-5-(trifluoromethyl)aniline

There total 5 articles about 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-YL)-5-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 510771-54-7
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2yl)-5-(trifluoromethyl)benzenamine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 90 ℃; for 16h; Inert atmosphere;

Reference yield: 69.0%

: 73183-34-3
bis(pinacol)diborane

: 54962-75-3
[3-bromo-5-(trifluoromethyl)phenyl]amine

: 510771-54-7
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2yl)-5-(trifluoromethyl)benzenamine

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In dimethyl sulfoxide; at 80 ℃; for 18h; Inert atmosphere;
DOI:10.1016/j.tet.2010.02.026

Reference yield:

: 4,4,5,5-tetramethyl-N-(3-(trifluoromethyl)phenyl)-1,3,2-dioxaborolan-2-amine

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 1196972-92-5
5-(trifluoromethyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine

: 510771-54-7
3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2yl)-5-(trifluoromethyl)benzenamine

Guidance literature:: 4,4,5,5-tetramethyl-N-(3-(trifluoromethyl)phenyl)-1,3,2-dioxaborolan-2-amine; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 3,4,7,8-Tetramethyl-o-phenanthrolin; In tetrahydrofuran; at 80 ℃; for 16h; Inert atmosphere; Glovebox;

With methanol; In tetrahydrofuran; at 20 ℃; Solvent; Inert atmosphere; Glovebox;
DOI:10.1002/anie.201306511