rifamide

Base Information

• Chemical Name: rifamide
• CAS No.: 2750-76-7
• Molecular Formula: C43H58 N2 O13
• Molecular Weight: 810.939
• European Community (EC) Number: 220-390-8
• UNII: TS121H7U7E
• DSSTox Substance ID: DTXSID901023450
• Wikidata: Q27290239
• NCI Thesaurus Code: C152215
• ChEMBL ID: CHEMBL3989415
• Mol file: 2750-76-7.mol

Synonyms:Acetamide,2-[(1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-9-yl)oxy]-N,N-diethyl-,21-acetate (7CI,8CI);2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, rifamycin deriv.; M14; M 14 (antibiotic); N,N-Diethylrifamycin B amide; NCI 143-418; NSC 133099;NSC 143418; Ribomycin B amide, N,N-diethyl-; Rifamide; Rifampicin M 14;Rifamycin B diethylamide; Rifamycin B, N,N-diethylamide; Rifamycin M14;Rifomide; Rifomycin B diethylamide; Rifomycin M14

Chemical Property of rifamide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 170°C (rough estimate)
• Refractive Index: 1.4670 (estimate)
• Boiling Point: 927.4°Cat760mmHg
• Flash Point: 514.7°C
• PSA: 210.62000
• Density: 1.3g/cm³
• LogP: 5.43370
• XLogP3: 5.5
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 8
• Exact Mass: 810.39388991
• Heavy Atom Count: 58
• Complexity: 1550

Purity/Quality:

95-99% ^*data from raw suppliers

RIFAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C(=O)COC1=C2C3=C(C(=C1)NC(=O)C(=CC=CC(C(C(C(C(C(C(C(C=COC4(C(=O)C2=C(O4)C(=C3O)C)C)OC)C)OC(=O)C)C)O)C)O)C)C)O
• Isomeric SMILES: CCN(CC)C(=O)COC1=C2C3=C(C(=C1)NC(=O)/C(=C\C=C\[C@@H]([C@@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]([C@H](/C=C/O[C@@]4(C(=O)C2=C(O4)C(=C3O)C)C)OC)C)OC(=O)C)C)O)C)O)C)/C)O
• Uses: Antibacterial.

Technology Process of rifamide

There total 1 articles about rifamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Rifamycin B (13929-35-6) + diethylamine (109-89-7) → Rifocin-M (2750-76-7)

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran;

DOI:10.1021/jm00335a005

upstream raw materials:

Rifamycin B

diethylamine