3,5-DiMethyl-2-pyridineMethanol Hydrochloride

Base Information

• Chemical Name: 3,5-DiMethyl-2-pyridineMethanol Hydrochloride
• CAS No.: 70580-28-8
• Molecular Formula: C8H12ClNO
• Molecular Weight: 173.63998
• Hs Code.: 2933399090
• Mol file: 70580-28-8.mol

Synonyms:3,5-DiMethyl-2-pyridineMethanol Hydrochloride

Chemical Property of 3,5-DiMethyl-2-pyridineMethanol Hydrochloride

Chemical Property:

• PSA: 33.12000
• LogP: 1.99270
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dimethyl-2-pyridinemethanolHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3,5-Dimethyl-2-pyridinemethanol Hydrochloride is an intermediate in the preparation of metabolites of Omeprazole (O635000), which Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.

Technology Process of 3,5-DiMethyl-2-pyridineMethanol Hydrochloride

There total 3 articles about 3,5-DiMethyl-2-pyridineMethanol Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,5-trimethyl-pyridine (695-98-7) → C8H11NO*ClH (70580-28-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 3-chloro-benzenecarboperoxoic acid / chloroform / 48 h / 20 °C / Inert atmosphere

2: 1.5 h / 100 °C / Inert atmosphere; Reflux

3: hydrogenchloride / water / 1 h / Inert atmosphere; Reflux

With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; In chloroform; water;

DOI:10.1021/jm2008369

Reference yield:

2,3,5-trimethylpyridine 1-oxide (74409-42-0) → C8H11NO*ClH (70580-28-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.5 h / 100 °C / Inert atmosphere; Reflux

2: hydrogenchloride / water / 1 h / Inert atmosphere; Reflux

With hydrogenchloride; In water;

DOI:10.1021/jm2008369

Reference yield:

acetic acid 3,5-dimethylpyridin-2-ylmethyl ester (206990-64-9) → C8H11NO*ClH (70580-28-8)

Guidance literature:

With hydrogenchloride; In water; for 1h; Inert atmosphere; Reflux;

DOI:10.1021/jm2008369

upstream raw materials:

2,3,5-trimethyl-pyridine

2,3,5-trimethylpyridine 1-oxide

acetic acid 3,5-dimethylpyridin-2-ylmethyl ester

Downstream raw materials:

2-chloromethyl-3,5-dimethylpyridine hydrochloride

Refernces