1-DIMETHYLAMINO-2-PROPYLAMINE 98

Base Information

• Chemical Name: 1-DIMETHYLAMINO-2-PROPYLAMINE 98
• CAS No.: 62689-51-4
• Molecular Formula: C₅H₁₄N₂
• Molecular Weight: 102.18
• Mol file: 62689-51-4.mol

Synonyms:1-DIMETHYLAMINO-2-PROPYLAMINE 98;(1)-N1,N1-Dimethylpropane-1,2-diamine;1,2-Propanediamine, N',N'-dimethyl-, (+-)-;1,2-Propanediamine, N1,N1-dimethyl-;Einecs 203-555-9;Einecs 263-699-3;Nsc 166323

Chemical Property of 1-DIMETHYLAMINO-2-PROPYLAMINE 98

Chemical Property:

• Vapor Pressure: 27.6mmHg at 25°C
• Melting Point: 35.18°C
• Refractive Index: n20/D 1.421(lit.)
• Boiling Point: 107°C at 760 mmHg
• Flash Point: 14.6°C
• Density: 0.834g/cm³

Purity/Quality:

99.3% ^*data from raw suppliers

Safty Information:

• Hazard Codes: C
• Statements: 22-37/38-41
• Safety Statements: 26-36/37/39-45

MSDS Files:

Useful:

Technology Process of 1-DIMETHYLAMINO-2-PROPYLAMINE 98

There total 16 articles about 1-DIMETHYLAMINO-2-PROPYLAMINE 98 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.8%

((R)-2-dimethylamino-1-methyl-ethyl)-carbamic acid tert-butyl ester → (2R)-N1,N1-dimethyl-1,2-propanediamine (346690-99-1,62689-51-4)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 20h;

Reference yield: 24.0%

dimethylaminoacetone (15364-56-4) → 1-(dimethylamino)-2-propylamine (108-15-6,346690-99-1,62689-51-4)

Guidance literature:

With ammonium acetate; sodium cyanoborohydride; magnesium sulfate; In methanol; Heating;

DOI:10.1016/j.bmcl.2008.01.015

Reference yield:

leucinostatin A (82111-44-2) → L-leucine (61-90-5,21675-61-6,25248-98-0,70-45-1) + (2S,3S)-3-hydroxyleucine (10148-70-6) + 2-Aminoisobutyric acid (62-57-7) + (2S)-N1,N1-dimethylpropane-1,2-diamine (70831-55-9,346690-99-1,62689-51-4)

Guidance literature:

With hydrogenchloride; at 110 ℃; for 20h; Further byproducts given;

DOI:10.1039/c39820000094

upstream raw materials:

dimethylaminoacetone

1-methyl-2-N,N-dimethylaminoethanol

P₁₆₈

L-N-Boc-Ala

Downstream raw materials:

N-((S)-2-Dimethylamino-1-methyl-ethyl)-benzamide

N-(1-methyl-2-dimethylaminoethyl)-2,2'-dihydroxy-diphenylketoimin

3-(4-chloro-phenethyl)-5-(2-dimethylamino-1-methyl-ethyl)-[1,3,5]thiadiazinane-2-thione

Refernces

• 1、 -. "NOVEL TRIFLUOROMETHYL-OXADIAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE". Page/Page column 94. . Retrieved 2013/03/26.
• 2、 Lavrado, Jo?o,Cabal, Ghislain G.,Prudêncio, Miguel,Mota, Maria M.,Gut, Jiri,Rosenthal, Philip J.,Díaz, Cecília,Guedes, Rita C.,Dos Santos, Daniel J. V. A.,Bichenkov?, Elena,Dougla?, Kenneth T.,Moreira, Rui,Paulo, Alexandra. "Incorporation of basic side chains into cryptolepine scaffold: Structure-antimalarial activity relationships and mechanistic studies". experimental part. p. 734 - 750. Retrieved 2011/04/15.