(R)-1-Phenylhexan-1-amine hydrochloride

Base Information

• Chemical Name: (R)-1-Phenylhexan-1-amine hydrochloride
• CAS No.: 211988-00-0
• Molecular Formula: C12H20ClN
• Molecular Weight: 213.7469
• DSSTox Substance ID: DTXSID20704139
• Mol file: 211988-00-0.mol

Synonyms:(R)-1-Phenylhexan-1-amine hydrochloride;211988-00-0;(R)-1-PHENYLHEXAN-1-AMINE-HCl;(R)-1-Phenylhexan-1-aminehydrochloride;(R)-1-phenylhexan-1-amine HCl;DTXSID20704139;AM9238;AKOS015922817;(1R)-1-phenylhexan-1-amine hydrochloride;CS-0449532;(1R)-1-Phenylhexan-1-amine--hydrogen chloride (1/1)

Chemical Property of (R)-1-Phenylhexan-1-amine hydrochloride

Chemical Property:

• PSA: 26.02000
• LogP: 4.76900
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 213.1284273
• Heavy Atom Count: 14
• Complexity: 116

Purity/Quality:

99%, ^*data from raw suppliers

(R)-1-Phenylhexan-1-aminehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC(C1=CC=CC=C1)N.Cl
• Isomeric SMILES: CCCCC[C@H](C1=CC=CC=C1)N.Cl

Technology Process of (R)-1-Phenylhexan-1-amine hydrochloride

There total 4 articles about (R)-1-Phenylhexan-1-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-2-[N-Methyl-N'-((R)-1-phenyl-hexyl)-hydrazino]-butan-1-ol → (R)-1-phenylhexan-1-amine (211988-00-0) + (S)-1-phenylhexan-1-amine

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; at 55 - 65 ℃; for 16h; under 4500.4 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1016/S0957-4166(98)00217-1

Reference yield:

n-pentylmagnesium bromide (693-25-4) → (R)-1-phenylhexan-1-amine (211988-00-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 81.4 percent / diethyl ether / 16 h / Heating

2: H₂, conc. HCl / 10percent Pd/C / ethanol / 16 h / 55 - 65 °C / 4500.4 Torr

With hydrogenchloride; hydrogen; palladium on activated charcoal; In diethyl ether; ethanol;

DOI:10.1016/S0957-4166(98)00217-1

Reference yield:

(R)-2-{N-Methyl-N'-[1-phenyl-meth-(E)-ylidene]-hydrazino}-butan-1-ol → (R)-1-phenylhexan-1-amine (211988-00-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 81.4 percent / diethyl ether / 16 h / Heating

2: H₂, conc. HCl / 10percent Pd/C / ethanol / 16 h / 55 - 65 °C / 4500.4 Torr

With hydrogenchloride; hydrogen; palladium on activated charcoal; In diethyl ether; ethanol;

DOI:10.1016/S0957-4166(98)00217-1

upstream raw materials:

n-pentylmagnesium bromide

C₁₆H₂₇NOS