6-Fluoro-3-methylquinoxalin-2(1H)-one

Base Information

Chemical Name:6-Fluoro-3-methylquinoxalin-2(1H)-one
CAS No.:98416-68-3
Molecular Formula:C₉H₇FN₂O
Molecular Weight:178.166
Hs Code.:2933990090
ChEMBL ID:CHEMBL5175274
DSSTox Substance ID:DTXSID10471025
Nikkaji Number:J2.234.314I
Wikidata:Q82299416
Mol file:98416-68-3.mol

Synonyms:98416-68-3;6-Fluoro-3-methylquinoxalin-2-ol;6-FLUORO-3-METHYLQUINOXALIN-2(1H)-ONE;CHEMBL5175274;6-fluoro-3-methyl-1H-quinoxalin-2-one;SCHEMBL14765152;DTXSID10471025;BDBM50591705;2(1H)-Quinoxalinone,6-fluoro-3-methyl-(9CI)

Suppliers and Price of 6-Fluoro-3-methylquinoxalin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
6-fluoro-3-methyl-2(1H)-Quinoxalinone 97.00%
25G
$ 7320.00

AccelPharmtech
6-fluoro-3-methyl-2(1H)-Quinoxalinone 97.00%
5G
$ 3900.00

AccelPharmtech
6-fluoro-3-methyl-2(1H)-Quinoxalinone 97.00%
1G
$ 2280.00

Total 5 raw suppliers

Chemical Property of 6-Fluoro-3-methylquinoxalin-2(1H)-one

Chemical Property:

PSA：45.75000
LogP:1.37060
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:178.05424101
Heavy Atom Count:13
Complexity:264

Purity/Quality:

99%+ ^*data from raw suppliers

6-fluoro-3-methyl-2(1H)-Quinoxalinone 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(C=CC(=C2)F)NC1=O

Technology Process of 6-Fluoro-3-methylquinoxalin-2(1H)-one

There total 9 articles about 6-Fluoro-3-methylquinoxalin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 146741-06-2
6-fluoro-3-methyl-3,4-dihydroquinoxalin-2(1H)-one

: 98416-68-3
6-fluoro-3-methyl-1H-quinoxalin-2-one

Guidance literature:: With dihydrogen peroxide; In sodium hydroxide; at 60 ℃; for 6h;
DOI:10.3987/COM-05-10461

Reference yield:

: 617-35-6
2-oxo-propionic acid ethyl ester

: 367-31-7
4-fluoro-1,2-phenylenediamine

: 311346-77-7
7-fluoro-3-methyl-1H-quinoxalin-2-one

: 98416-68-3
6-fluoro-3-methyl-1H-quinoxalin-2-one

Guidance literature:: In methanol; for 0.166667h; Overall yield = 7.3 g; Reflux;

Reference yield:

: 868771-38-4
N-(2-amino-4-fluoro-phenyl)-2-chloro-propionamide

: 98416-68-3
6-fluoro-3-methyl-1H-quinoxalin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 48 percent / NaI*2H₂O; NaHCO₃ / acetonitrile / 15 h / Heating

2: 88 percent / aq. H₂O₂ / aq. NaOH / 6 h / 60 °C

With dihydrogen peroxide; sodium hydrogencarbonate; sodium iodide; In sodium hydroxide; acetonitrile;
DOI:10.3987/COM-05-10461