5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine

Base Information

Chemical Name:5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
CAS No.:1363380-51-1
Molecular Formula:C6H3ClN4O2
Molecular Weight:198.568
Hs Code.:2933990090
Mol file:1363380-51-1.mol

Synonyms:5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine;5-Chloro-3-nitropyrazolo[...

Suppliers and Price of 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
5-Chloro-3-nitropyrazolo[1,5-A]pyrimidine
5g
$ 228.00

Alichem
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine
1g
$ 732.25

Alichem
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine
5g
$ 1386.00

Ambeed
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 95%
25g
$ 430.00

Ambeed
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 95%
5g
$ 142.00

Ambeed
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 95%
100mg
$ 7.00

Ambeed
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 95%
250mg
$ 11.00

Ambeed
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 95%
1g
$ 32.00

American Custom Chemicals Corporation
5-CHLORO-3-NITROPYRAZOLO[1,5-A]PYRIMIDINE 95.00%
5MG
$ 504.34

Apolloscientific
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine 97%
1g
$ 85.00

Total 56 raw suppliers

Chemical Property of 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine

Chemical Property:

PKA:-3.59±0.40(Predicted)
PSA：76.01000
Density:1.85±0.1 g/cm3(Predicted)
LogP:1.81410
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Chloroform (Slightly, Heated), DMSO (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

5-Chloro-3-nitropyrazolo[1,5-A]pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine is used in the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, a tyrosine kinase (TRK) inhibitor for treating cancer.

Technology Process of 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine

There total 5 articles about 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.2%

: C₆H₄N₄O₃

: 1363380-51-1
5-chloro-3-nitropyrazolo[1,5-a]pyrimidine

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; chlorobenzene; at 100 ℃; Temperature; Reagent/catalyst; Solvent; Inert atmosphere;