N-Butyl-N,4-dimethylbenzenesulfonamide

Base Information

• Chemical Name: N-Butyl-N,4-dimethylbenzenesulfonamide
• CAS No.: 10285-91-3
• Molecular Formula: C12H19NO2S
• Molecular Weight: 241.35
• Mol file: 10285-91-3.mol

Synonyms:N-Butyl-N,4-dimethylbenzenesulfonamide

Chemical Property of N-Butyl-N,4-dimethylbenzenesulfonamide

Chemical Property:

• Boiling Point: 110 - 112 °C (0.02 mmHg)
• PSA: 45.76000
• LogP: 3.49640

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Butyl-N,4-dimethylbenzenesulfonamide

There total 6 articles about N-Butyl-N,4-dimethylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

butan-1-ol (71-36-3) + N-methyl-p-toluenesulfonylamide (640-61-9) → N-butyl-N-methyl-4-methylbenzenesulfonamide (10285-91-3)

Guidance literature:

With tributylphosphine; diamide; In benzene; for 24h; Ambient temperature;

DOI:10.1246/cl.1994.539 DOI:10.1016/S0040-4039(00)73326-0

Reference yield: 86.0%

N,N-dimethylbutylamine (927-62-8) + sodium 4-methylbenzenesulfinate (824-79-3) → N-butyl-N-methyl-4-methylbenzenesulfonamide (10285-91-3)

Guidance literature:

With tert.-butylhydroperoxide; iodine; In water; at 80 ℃; for 8h; Sealed tube;

DOI:10.1021/acs.orglett.6b01412

Reference yield: 77.0%

dibutyl ether (142-96-1) + N-methyl-p-toluenesulfonylamide (640-61-9) → N-butyl-N-methyl-4-methylbenzenesulfonamide (10285-91-3)

Guidance literature:

With titanium tetrachloride; In 1,1,2,2-tetrachloroethane; at 120 ℃; for 48h; sealed tube;

DOI:10.1055/s-0031-1290332

upstream raw materials:

N-methyl-p-toluenesulfonylamide

butan-1-ol

dibutyl ether

p-toluenesulfonyl chloride