(5-(4-Bromophenyl)isoxazol-3-yl)methanol

Base Information

Chemical Name:(5-(4-Bromophenyl)isoxazol-3-yl)methanol
CAS No.:640291-96-9
Molecular Formula:C10H8BrNO2
Molecular Weight:254.083
Hs Code.:2934999090
European Community (EC) Number:621-843-6
DSSTox Substance ID:DTXSID00586430
Wikidata:Q82478563
Mol file:640291-96-9.mol

Synonyms:(5-(4-bromophenyl)isoxazol-3-yl)methanol;640291-96-9;[5-(4-Bromophenyl)-1,2-oxazol-3-yl]methanol;SCHEMBL5502;DTXSID00586430;RLIPRZYWGPFTQY-UHFFFAOYSA-N;MFCD06199340;AKOS002671681;MCULE-4784854810;DB-009007;CS-0089008;[5-(4-Bromo-phenyl)-isoxazol-3-yl]-methanol;D74787;(5-(4-BROMOPHENYL)-3-ISOXAZOLYL)METHANOL

Suppliers and Price of (5-(4-Bromophenyl)isoxazol-3-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(5-(4-BROMOPHENYL)ISOXAZOL-3-YL)METHANOL 95.00%
10G
$ 7882.88

American Custom Chemicals Corporation
(5-(4-BROMOPHENYL)ISOXAZOL-3-YL)METHANOL 95.00%
5G
$ 4244.63

American Custom Chemicals Corporation
(5-(4-BROMOPHENYL)ISOXAZOL-3-YL)METHANOL 95.00%
1G
$ 1030.84

Abosyn
(5-(4-bromophenyl)isoxazol-3-yl)methanol 95%-98%
1g
$ 712.00

Total 4 raw suppliers

Chemical Property of (5-(4-Bromophenyl)isoxazol-3-yl)methanol

Chemical Property:

PSA：46.26000
LogP:2.59640
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:252.97384
Heavy Atom Count:14
Complexity:183

Purity/Quality:

NLT 98% ^*data from raw suppliers

(5-(4-BROMOPHENYL)ISOXAZOL-3-YL)METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC(=NO2)CO)Br

Technology Process of (5-(4-Bromophenyl)isoxazol-3-yl)methanol

There total 4 articles about (5-(4-Bromophenyl)isoxazol-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 33277-15-5
ethyl 5-(4-bromo-phenyl)-isoxazole-3-carboxylate

: 640291-96-9
[5-(4-bromo-phenyl)-isoxazol-3-yl]-methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h;

Reference yield:

: 40155-54-2
ethyl 4-(4-bromophenyl)-2,4-dioxobutanoate

: 640291-96-9
[5-(4-bromo-phenyl)-isoxazol-3-yl]-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: NH₂OH*HCl / ethanol / 1 h / Heating

2: LiAlH₄ / diethyl ether / 0.5 h / 40 °C

With lithium aluminium tetrahydride; hydroxylamine hydrochloride; In diethyl ether; ethanol;
DOI:10.1055/s-2003-41072

Reference yield:

: 99-90-1
para-bromoacetophenone

: 640291-96-9
[5-(4-bromo-phenyl)-isoxazol-3-yl]-methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / toluene / 45 - 50 °C

1.2: toluene / 1.5 h / Heating

2.1: NH₂OH*HCl / ethanol / 1 h / Heating

3.1: LiAlH₄ / diethyl ether / 0.5 h / 40 °C

With lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium hydride; In diethyl ether; ethanol; toluene;
DOI:10.1055/s-2003-41072