SUCCINIMIDYL NERVONATE

Base Information

• Chemical Name: SUCCINIMIDYL NERVONATE
• CAS No.: 191354-88-8
• Molecular Formula: C28H49NO4
• Molecular Weight: 463.69
• Mol file: 191354-88-8.mol

Synonyms:SUCCINIMIDYL NERVONATE;(15Z)-15-Tetracosenoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester;1-[[(15Z)-1-Oxo-15-tetracosenyl]oxy]-2,5-pyrrolidinedione

Chemical Property of SUCCINIMIDYL NERVONATE

Chemical Property:

• Melting Point: 53-54°C
• Boiling Point: 545.3±33.0 °C(Predicted)
• PSA: 63.68000
• Density: 0.99±0.1 g/cm3(Predicted)
• LogP: 7.90960
• Storage Temp.: -20°C Freezer
• Solubility.: Dichloromethane, Hot Ethanol, Ethyl Acetate, Methanol

Purity/Quality:

97% ^*data from raw suppliers

Succinimidyl Nervonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Succinimidyl Nervonate (cas# 191354-88-8) is a compound useful in organic synthesis.

Technology Process of SUCCINIMIDYL NERVONATE

There total 1 articles about SUCCINIMIDYL NERVONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + Nervonic acid (506-37-6) → nervonic acid N-hydroxysuccinimide ester (191354-88-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In ethyl acetate;

DOI:10.1016/S0009-3084(97)00042-X

Reference yield: 91.0%

(2S,3R,4E)-2-amino-4-octadecene-1,3-diol (123-78-4) + nervonic acid N-hydroxysuccinimide ester (191354-88-8) → N-(15Z-tetracosenoyl)-sphing-4-enine (54164-50-0)

Guidance literature:

In tetrahydrofuran;

DOI:10.1016/S0009-3084(97)00042-X

Reference yield:

nervonic acid N-hydroxysuccinimide ester (191354-88-8) → 1-O-triphenylmethyl-24:1-Cer (124751-47-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / tetrahydrofuran

2: 72 percent / N,N-dimethyl-4-aminopyridine / toluene / 16 h / Heating

With dmap; In tetrahydrofuran; toluene;

DOI:10.1016/S0009-3084(97)00042-X

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

Nervonic acid

Downstream raw materials:

N-(15Z-tetracosenoyl)-sphing-4-enine

1-O-triphenylmethyl-24:1-Cer