6,7-DIMETHYLCHROMONE

Base Information

• Chemical Name: 6,7-DIMETHYLCHROMONE
• CAS No.: 288399-56-4
• Molecular Formula: C₁₁H₁₀O₂
• Molecular Weight: 174.199
• Mol file: 288399-56-4.mol

Synonyms:6,7-DIMETHYLCHROMONE;4H-1-Benzopyran-4-one, 6,7-diMethyl-

Chemical Property of 6,7-DIMETHYLCHROMONE

Chemical Property:

• PSA: 30.21000
• LogP: 2.40980

Purity/Quality:

97-99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,7-DIMETHYLCHROMONE

There total 1 articles about 6,7-DIMETHYLCHROMONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-acetyl-4,5-dimethylphenol (36436-65-4) + formic acid ethyl ester (109-94-4) → 6,7-dimethylchromone (288399-56-4)

Guidance literature:

2-acetyl-4,5-dimethylphenol; formic acid ethyl ester; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 4h;

With hydrogenchloride; In tetrahydrofuran; methanol; mineral oil; at 0 - 20 ℃;

DOI:10.1002/asia.201403290

Reference yield: 72.0%

6,7-dimethylchromone (288399-56-4) + phenylboronic acid (98-80-6) → C17H16O2

Guidance literature:

With chlorobis(ethylene)rhodium(I) dimer; potassium hydroxide; (1R,4R)-2,5-diphenylbicyclo[2.2.2]octa-2,5-diene; In 1,4-dioxane; water; at 90 ℃; for 22h; enantioselective reaction; Inert atmosphere;

DOI:10.1002/asia.201403290

Reference yield:

6,7-dimethylchromone (288399-56-4) + phenylboronic acid (98-80-6) → 6,7-dimethyl-2-phenylchroman-4-one (65249-14-1)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; potassium hydroxide; In 1,4-dioxane; water; at 100 ℃; for 16h;

DOI:10.1002/asia.201403290

upstream raw materials:

2-acetyl-4,5-dimethylphenol

formic acid ethyl ester

Downstream raw materials:

6,7-dimethyl-2-phenylchroman-4-one