5-[(4-METHOXYPHENYL)METHOXY]-3-OXO-PENTANOIC ACID METHYL ESTER

Base Information

Chemical Name:5-[(4-METHOXYPHENYL)METHOXY]-3-OXO-PENTANOIC ACID METHYL ESTER
CAS No.:118207-58-2
Molecular Formula:C14H18O5
Molecular Weight:266.294
Hs Code.:
Mol file:118207-58-2.mol

Synonyms:5-[(4-METHOXYPHENYL)METHOXY]-3-OXO-PENTANOIC ACID METHYL ESTER

Suppliers and Price of 5-[(4-METHOXYPHENYL)METHOXY]-3-OXO-PENTANOIC ACID METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[(4-METHOXYPHENYL)METHOXY]-3-OXO-PENTANOIC ACID METHYL ESTER

Chemical Property:

PSA：61.83000
LogP:1.73410

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-[(4-METHOXYPHENYL)METHOXY]-3-OXO-PENTANOIC ACID METHYL ESTER

There total 4 articles about 5-[(4-METHOXYPHENYL)METHOXY]-3-OXO-PENTANOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 218434-91-4
5-(4-Methoxy-benzyloxy)-pent-2-ynoic acid methyl ester

: 118207-58-2
5-(4-methoxybenzyloxy)-3-oxopentanoic acid methyl ester

Guidance literature:: With syn-benzaldehyde oxime; sodium hydride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃; for 1h;
DOI:10.1021/ol025861m

Reference yield:

: 96-32-2
bromoacetic acid methyl ester

: 3-(4-methoxybenzyloxy)propanenitrile

: 118207-58-2
5-(4-methoxybenzyloxy)-3-oxopentanoic acid methyl ester

Guidance literature:: bromoacetic acid methyl ester; 3-(4-methoxybenzyloxy)propanenitrile; With zinc; In tetrahydrofuran; for 2h; Inert atmosphere; Reflux;

With acetic acid; In tetrahydrofuran; water; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jacs.8b03063

Reference yield:

: 105-13-5
4-Methoxybenzyl alcohol

: 118207-58-2
5-(4-methoxybenzyloxy)-3-oxopentanoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water / 15 h / 20 °C / Inert atmosphere

2.1: zinc / tetrahydrofuran / 2 h / Inert atmosphere; Reflux

2.2: 1 h / 20 °C / Inert atmosphere

With sodium hydroxide; zinc; In tetrahydrofuran; water;
DOI:10.1021/jacs.8b03063