Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate

Base Information

Chemical Name:Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate
CAS No.:7767-60-4
Molecular Formula:C₈H₈O₂S₂
Molecular Weight:200.282
Hs Code.:
DSSTox Substance ID:DTXSID10392509
Wikidata:Q82190821
Mol file:7767-60-4.mol

Synonyms:methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate;7767-60-4;4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylic Acid Methyl Ester;4,6-Dihydro-thieno[3,4-b]thiophene-2-carboxylic acid methyl ester;SCHEMBL1659891;DTXSID10392509;HHUQUYKPAMERGU-UHFFFAOYSA-N;AMY24297;MFCD15096514;DS-18981;CS-0042854;FT-0735387;M2202;C76487;A917283;methyl4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate

Suppliers and Price of Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate
100mg
$ 316.00

TRC
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate
50mg
$ 90.00

TCI Chemical
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate >98.0%(GC)
1g
$ 411.00

Crysdot
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate 95%
1g
$ 277.00

Crysdot
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate 95%
10g
$ 1337.00

Crysdot
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate 95%
5g
$ 832.00

Chem-Impex
Methyl4,6-dihydrothieno[3,4-β]thiophene-2-carboxylate,≥98%(GC) ≥98%(GC)
25G
$ 530.40

Ambeed
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate 95%
1g
$ 75.00

Ambeed
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate 95%
250mg
$ 30.00

Ambeed
Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate 95%
100mg
$ 19.00

Total 12 raw suppliers

Chemical Property of Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate

Chemical Property:

Melting Point:95.0 to 99.0 °C
Boiling Point:371.2±42.0 °C(Predicted)
PSA：79.84000
Density:1.377±0.06 g/cm3(Predicted)
LogP:2.28150
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:199.99657184
Heavy Atom Count:12
Complexity:196

Purity/Quality:

97% ^*data from raw suppliers

Methyl 4,6-Dihydrothieno[3,4-b]thiophene-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC2=C(S1)CSC2

Technology Process of Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate

There total 3 articles about Methyl 4,6-dihydrothieno[3,4-b]thiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 7353-89-1
4,5-Bis-chloromethyl-thiophene-2-carboxylic acid methyl ester

: 7767-60-4
4,6-Dihydro-thieno[3,4-b]thiophene-2-carboxylic acid methyl ester

Guidance literature:: With sodium sulfide; In methanol; at 70 ℃; for 5h;

Reference yield:

: 5380-42-7
thiophene-2-carboxylic acid methyl ester

: 7767-60-4
4,6-Dihydro-thieno[3,4-b]thiophene-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: titanium tetrachloride / 5 h / Inert atmosphere; Cooling with ice

2: sodium sulfide / methanol / 2 h / Reflux

With sodium sulfide; titanium tetrachloride; In methanol;

Reference yield:

: 7767-60-4
4,6-Dihydro-thieno[3,4-b]thiophene-2-carboxylic acid methyl ester

Guidance literature:: 2,3-Bis-chlormethyl-thiophen-2-carbonsaeure-methylester (VI) in Methanol, NaS in Methanol (aus Na in Methanol und H2S);
DOI:10.1021/jo01348a058