N-tert-Butyloxycarbonyl Silodosin

Base Information

Chemical Name:N-tert-Butyloxycarbonyl Silodosin
CAS No.:160970-07-0
Molecular Formula:
Molecular Weight:595.65
Hs Code.:
Mol file:160970-07-0.mol

Synonyms:N-tert-Butyloxycarbonyl Silodosin

Suppliers and Price of N-tert-Butyloxycarbonyl Silodosin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-tert-ButyloxycarbonylSilodosin
50mg
$ 165.00

Medical Isotopes, Inc.
N-tert-ButyloxycarbonylSilodosin
500 mg
$ 2200.00

Total 1 raw suppliers

Chemical Property of N-tert-Butyloxycarbonyl Silodosin

Chemical Property:

Boiling Point:663.7±55.0 °C(Predicted)
PKA:14.85±0.10(Predicted)
Density:1.237±0.06 g/cm3(Predicted)
Solubility.:Dichloromethane, Ethyl Acetate, Tetrahydrofuran

Purity/Quality:: N-tert-ButyloxycarbonylSilodosin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses N-tert-Butyloxycarbonyl Silodosin is a protected Silodosin (S465000), an α1a-adrenoceptor antagonist.

Technology Process of N-tert-Butyloxycarbonyl Silodosin

There total 7 articles about N-tert-Butyloxycarbonyl Silodosin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1427271-99-5
(R)-tert-butyl(1-(7-cyano-1-(3-hydroxypropyl)indolin-5-yl)propan-2-yl)(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate

: 160970-07-0
(R)-tert-butyl 1-(7-carbamoyl-1-(3-hydroxypropyl)indolin-5-yl)propan-2-yl(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate

Guidance literature:: With dihydrogen peroxide; sodium hydroxide; In dimethyl sulfoxide; at 20 - 25 ℃; for 12h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 160970-54-7,2182279-45-2
silodosin

: 160970-07-0
(R)-tert-butyl 1-(7-carbamoyl-1-(3-hydroxypropyl)indolin-5-yl)propan-2-yl(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate

Guidance literature:: In dichloromethane; ethyl acetate;

Reference yield:

: 1-[3-(benzoyloxy)propyl]-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carbonitrile ethanedioate

: 160970-07-0
(R)-tert-butyl 1-(7-carbamoyl-1-(3-hydroxypropyl)indolin-5-yl)propan-2-yl(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: ammonium hydroxide / dichloromethane; water

1.2: 12 h / 0 - 20 °C

2.1: potassium hydroxide / methanol / 12 h / 10 - 20 °C

3.1: dihydrogen peroxide; sodium hydroxide / dimethyl sulfoxide / 12 h / 20 - 25 °C

With ammonium hydroxide; dihydrogen peroxide; potassium hydroxide; sodium hydroxide; In methanol; dichloromethane; water; dimethyl sulfoxide;