4-Chloro-7-[2-(2-methoxyethoxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidine

Base Information

Chemical Name:4-Chloro-7-[2-(2-methoxyethoxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidine
CAS No.:186519-96-0
Molecular Formula:C₁₁H₁₄ClN₃O₂
Molecular Weight:255.704
Hs Code.:
DSSTox Substance ID:DTXSID001169766
Nikkaji Number:J977.995G
Mol file:186519-96-0.mol

Synonyms:186519-96-0;7-(2-(2-methoxyethoxy)ethyl)-4-chloro-7h-pyrrolo[2,3-d]pyrimidine;4-chloro-7-[2-(2-methoxyethoxy)ethyl]pyrrolo[2,3-d]pyrimidine;4-Chloro-7-[2-(2-methoxyethoxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidine;SCHEMBL7028699;DTXSID001169766;4-chloro-7-[2-(2-methoxy-ethoxy)-ethyl]-7H-pyrrolo[2,3-d]pyrimidine

Suppliers and Price of 4-Chloro-7-[2-(2-methoxyethoxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
7-(2-(2-METHOXYETHOXY)ETHYL)-4-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE 95.00%
5MG
$ 498.38

Total 1 raw suppliers

Chemical Property of 4-Chloro-7-[2-(2-methoxyethoxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidine

Chemical Property:

PSA：0.00000
LogP:0.00000
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:255.0774544
Heavy Atom Count:17
Complexity:233

Purity/Quality:: 7-(2-(2-METHOXYETHOXY)ETHYL)-4-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COCCOCCN1C=CC2=C1N=CN=C2Cl

Technology Process of 4-Chloro-7-[2-(2-methoxyethoxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidine

There total 2 articles about 4-Chloro-7-[2-(2-methoxyethoxy)ethyl]-7H-pyrrolo[2,3-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 111-77-3,95507-80-5
2-(2-methoxyethoxy)ethyl alcohol

: 186519-89-1
7-(benzenesulfonyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

: 186519-96-0
4-chloro-7-[2-(2-methoxy-ethoxy)-ethyl]-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: With sodium hydride; potassium carbonate; In toluene; at 110 ℃; for 24h;
DOI:10.1016/S0040-4039(98)01146-0

Reference yield:

: 3680-69-1
4-chloro-1H-pyrrolo[2,3-d]pyrimidine

: 186519-96-0
4-chloro-7-[2-(2-methoxy-ethoxy)-ethyl]-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / tetrahydrofuran

2: 90 percent / NaH, K₂CO₃ / toluene / 24 h / 110 °C

With sodium hydride; potassium carbonate; In tetrahydrofuran; toluene;
DOI:10.1016/S0040-4039(98)01146-0