2',7-Dichloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione

Base Information

Chemical Name:2',7-Dichloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
CAS No.:26881-56-1
Molecular Formula:C16H14Cl2O5
Molecular Weight:357.19
Hs Code.:
Mol file:26881-56-1.mol

Synonyms:2',7-Dichloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione

Suppliers and Price of 2',7-Dichloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2',7-Dichloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione

Chemical Property:

Boiling Point:558.9±50.0 °C(Predicted)
PSA：61.83000
Density:1.46±0.1 g/cm3(Predicted)
LogP:3.40270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2',7-Dichloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione

There total 4 articles about 2',7-Dichloro-4,6-dimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1158186-19-6
griseofulvic acid

: 26881-56-1
(6'R)-(7-chloro-4,6-dimethoxy-benzofuran-3-one)-2-spiro-1'-(2'-chloro-6'-methyl-cyclohex-2'-en-4'-one)

: 1235-50-3
(2S,6'R)-(7-chloro-4,6-dimethoxy-benzofuran-3-one)-2-spiro-1'-(4'-chloro-6'-methylcyclohex-3'-ene-2'-one)

Guidance literature:: With lithium chloride; trichlorophosphate; In 1,4-dioxane; at 100 ℃; for 0.5h;
DOI:10.1021/jm200835c

Reference yield:

: 126-07-8
griseofulvin

: 26881-56-1
(6'R)-(7-chloro-4,6-dimethoxy-benzofuran-3-one)-2-spiro-1'-(2'-chloro-6'-methyl-cyclohex-2'-en-4'-one)

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; acetic acid

2: lithium chloride; trichlorophosphate / 1,4-dioxane / 0.5 h / 100 °C

With sulfuric acid; acetic acid; lithium chloride; trichlorophosphate; In 1,4-dioxane;
DOI:10.1021/jm200835c