8-Fluoro-2-phenylquinolin-4(1H)-one

Base Information

Chemical Name:8-Fluoro-2-phenylquinolin-4(1H)-one
CAS No.:1070879-73-0
Molecular Formula:C₁₅H₁₀FNO
Molecular Weight:239.249
Hs Code.:
ChEMBL ID:CHEMBL15450
DSSTox Substance ID:DTXSID80566013
Nikkaji Number:J548.609B
Wikidata:Q82451420
Mol file:1070879-73-0.mol

Synonyms:1070879-73-0;CHEMBL15450;8-Fluoro-2-phenyl-1H-quinolin-4-one;8-Fluoro-2-phenylquinolin-4(1H)-one;8-Fluoro-2-phenyl-4-quinolinol;SCHEMBL10865346;8-fluoro-2-phenylquinolin-4-ol;DTXSID80566013;BDBM50044968;MFCD11505232;8-Fluoro-4-hydroxy-2-phenylquinoline

Suppliers and Price of 8-Fluoro-2-phenylquinolin-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8-FLUORO-4-HYDROXY-2-PHENYLQUINOLINE 95.00%
25MG
$ 704.55

Total 3 raw suppliers

Chemical Property of 8-Fluoro-2-phenylquinolin-4(1H)-one

Chemical Property:

PSA：33.12000
LogP:3.74650
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:239.074642105
Heavy Atom Count:18
Complexity:360

Purity/Quality:

97% ^*data from raw suppliers

8-FLUORO-4-HYDROXY-2-PHENYLQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)C3=C(N2)C(=CC=C3)F

Technology Process of 8-Fluoro-2-phenylquinolin-4(1H)-one

There total 3 articles about 8-Fluoro-2-phenylquinolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (Z)-3-(2-Fluoro-phenylamino)-3-phenyl-acrylic acid ethyl ester

: 1070879-73-0,147197-83-9
8-Fluoro-2-phenyl-1H-quinolin-4-one

Guidance literature:: In diphenylether; at 240 - 250 ℃; for 0.166667h; Yield given;
DOI:10.1021/jm00061a005

Reference yield:

: 348-54-9
2-Fluoroaniline

: 1070879-73-0,147197-83-9
8-Fluoro-2-phenyl-1H-quinolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: AcOH / ethanol / 24 h / 50 °C

2: diphenyl ether / 0.17 h / 240 - 250 °C

With acetic acid; In diphenylether; ethanol;
DOI:10.1021/jm00061a005

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 1070879-73-0,147197-83-9
8-Fluoro-2-phenyl-1H-quinolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: AcOH / ethanol / 24 h / 50 °C

2: diphenyl ether / 0.17 h / 240 - 250 °C

With acetic acid; In diphenylether; ethanol;
DOI:10.1021/jm00061a005