3-Amino-3-(2,5-dimethylthiophen-3-yl)propanoic acid

Base Information

Chemical Name:3-Amino-3-(2,5-dimethylthiophen-3-yl)propanoic acid
CAS No.:470704-56-4
Molecular Formula:C₉H₁₃NO₂S
Molecular Weight:199.274
Hs Code.:
DSSTox Substance ID:DTXSID10697263
Mol file:470704-56-4.mol

Synonyms:470704-56-4;3-amino-3-(2,5-dimethylthiophen-3-yl)propanoic acid;3-AMINO-3-(2,5-DIMETHYL-THIOPHEN-3-YL)-PROPIONIC ACID;DTXSID10697263;AKOS010815818;CS-0345619;EN300-1283890;3-AMINO-3-(2,5-DIMETHYL-THIOPHEN-3-YL)-PROPIONICACID

Suppliers and Price of 3-Amino-3-(2,5-dimethylthiophen-3-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-Amino-3-(2,5-dimethyl-thiophen-3-yl)-propionicacid 95
25g
$ 4550.00

Labseeker
3-Amino-3-(2,5-dimethyl-thiophen-3-yl)-propionicacid 95
5g
$ 2750.00

American Custom Chemicals Corporation
3-AMINO-3-(2,5-DIMETHYL-THIOPHEN-3-YL)-PROPIONIC ACID 95.00%
5MG
$ 496.21

Total 2 raw suppliers

Chemical Property of 3-Amino-3-(2,5-dimethylthiophen-3-yl)propanoic acid

Chemical Property:

PSA：91.56000
LogP:2.53970
XLogP3:-1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:199.06669983
Heavy Atom Count:13
Complexity:198

Purity/Quality:

99% ^*data from raw suppliers

3-Amino-3-(2,5-dimethyl-thiophen-3-yl)-propionicacid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(S1)C)C(CC(=O)O)N

Technology Process of 3-Amino-3-(2,5-dimethylthiophen-3-yl)propanoic acid

There total 3 articles about 3-Amino-3-(2,5-dimethylthiophen-3-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 26421-44-3
2,5-dimethyl-thiophene-3-carbaldehyde

: 141-82-2
malonic acid

: 470704-56-4
3-amino-3-(2,5-dimethylthien-3-yl)propanoic acid

Guidance literature:: With ammonium acetate; In ethanol; for 24h; Heating;
DOI:10.1016/S0968-0896(02)00070-6

Reference yield:

: 638-02-8
2,5-DIMETHYLTHIOPHENE

: 470704-56-4
3-amino-3-(2,5-dimethylthien-3-yl)propanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃ / 3.5 h / 20 - 80 °C

2: aq. NaOH / dimethylformamide / 10 °C / pH 10

3: 53 percent / NH₄OAc / ethanol / 24 h / Heating

With sodium hydroxide; ammonium acetate; trichlorophosphate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(02)00070-6

Reference yield:

: [chloro-(2,5-dimethyl-thiophen-3-yl)-methyl]-dimethyl-amine

: 470704-56-4
3-amino-3-(2,5-dimethylthien-3-yl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / dimethylformamide / 10 °C / pH 10

2: 53 percent / NH₄OAc / ethanol / 24 h / Heating

With sodium hydroxide; ammonium acetate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0968-0896(02)00070-6