Cyclohexanone, 5-methyl-2-(1-methylethyl)-, oxime, (2R,5S)- (9CI)

Base Information

• Chemical Name: Cyclohexanone, 5-methyl-2-(1-methylethyl)-, oxime, (2R,5S)- (9CI)
• CAS No.: 165874-36-2
• Molecular Formula: C₁₀H₁₉NO
• Molecular Weight: 169.267
• Mol file: 165874-36-2.mol

Synonyms:Cyclohexanone, 5-methyl-2-(1-methylethyl)-, oxime, (2R,5S)- (9CI)

Chemical Property of Cyclohexanone, 5-methyl-2-(1-methylethyl)-, oxime, (2R,5S)- (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohexanone, 5-methyl-2-(1-methylethyl)-, oxime, (2R,5S)- (9CI)

There total 17 articles about Cyclohexanone, 5-methyl-2-(1-methylethyl)-, oxime, (2R,5S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(2R,5S)-menthone (10458-14-7,14073-97-3,17627-49-5,7786-64-3) → (1R,5S)-menthone oxime (65620-72-6,165874-36-2)

Guidance literature:

With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; at 20 ℃; for 24h;

DOI:10.1021/acsmedchemlett.1c00001

Reference yield: 95.0%

2-(2-isopropyl-5-methylcyclohexyloxy)tetrahydro-2H-pyran (72020-06-5,80924-03-4,97526-56-2,123121-06-2,128946-28-1,128946-29-2,128946-30-5,128946-31-6,134052-28-1) → p-menthan-3-one oxime (1198-91-0,21002-69-7,26134-50-9,37886-68-3,49775-31-7,49805-45-0,49805-46-1,49805-47-2,65620-72-6,114129-78-1,19096-86-7,165874-36-2)

Guidance literature:

With trichloroisocyanuric acid; hydroxylamine hydrochloride; In neat (no solvent); at 110 ℃; for 1h; Green chemistry;

DOI:10.1080/10426507.2014.990015

Reference yield: 95.0%

(2R,5S)-menthone (10458-14-7,14073-97-3,17627-49-5,7786-64-3) → (-)-(E)-(1R,4S)-menthyl oxime (37886-68-3,165874-36-2)

Guidance literature:

With hydroxylamine hydrochloride; sodium dodecyl-sulfate; sodium carbonate; In water; for 48h; Ambient temperature;

upstream raw materials:

(-)-menthol

(2R,5S)-menthone

3-Chlor-3-nitroso-1-methyl-4-isopropyl-cyclohexan

trimethylaluminum

Downstream raw materials:

N-neomenthyl-benzamide

(+)-neomenthylamine

p-menthan-3-one-(O-benzoyl oxime )

(3S,6R)-3-isopropyl-6-methylhexahydroazepin-2-one