[1-(4-Fluorobenzyl)piperidin-4-yl]methylamine

Base Information

Chemical Name:[1-(4-Fluorobenzyl)piperidin-4-yl]methylamine
CAS No.:174561-02-5
Molecular Formula:C13H19FN2
Molecular Weight:222.3017632
Hs Code.:
DSSTox Substance ID:DTXSID30409426
Mol file:174561-02-5.mol

Synonyms:174561-02-5;[1-(4-fluorobenzyl)piperidin-4-yl]methylamine;1-[1-(4-fluorobenzyl)piperidin-4-yl]methanamine;(1-(4-Fluorobenzyl)piperidin-4-yl)methanamine;[1-[(4-fluorophenyl)methyl]piperidin-4-yl]methanamine;1-{1-[(4-FLUOROPHENYL)METHYL]PIPERIDIN-4-YL}METHANAMINE;1-[1-(4-fluorobenzyl)piperidin-4-yl]methanamine(SALTDATA: FREE);SCHEMBL6536154;DTXSID30409426;MFCD06809642;AKOS000210668;LS-02137;BB 0257058;CS-0316417;J-011009

Suppliers and Price of [1-(4-Fluorobenzyl)piperidin-4-yl]methylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[1-(4-fluorobenzyl)piperidin-4-yl]methanamine
50mg
$ 65.00

Matrix Scientific
[1-(4-Fluorobenzyl)piperidin-4-yl]methylamine
500mg
$ 189.00

Crysdot
(1-(4-Fluorobenzyl)piperidin-4-yl)methanamine 95+%
5g
$ 752.00

American Custom Chemicals Corporation
[1-(4-FLUOROBENZYL)PIPERIDIN-4-YL]METHYLAMINE 95.00%
5G
$ 1328.25

American Custom Chemicals Corporation
[1-(4-FLUOROBENZYL)PIPERIDIN-4-YL]METHYLAMINE 95.00%
1G
$ 750.75

American Custom Chemicals Corporation
[1-(4-FLUOROBENZYL)PIPERIDIN-4-YL]METHYLAMINE 95.00%
0.5G
$ 682.00

AK Scientific
[1-(4-Fluorobenzyl)piperidin-4-yl]methylamine
500mg
$ 305.00

Total 5 raw suppliers

Chemical Property of [1-(4-Fluorobenzyl)piperidin-4-yl]methylamine

Chemical Property:

Boiling Point:308.1±17.0 °C(Predicted)
PKA:10.13±0.29(Predicted)
PSA：29.26000
Density:1.085±0.06 g/cm3(Predicted)
LogP:2.63460
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:222.15322678
Heavy Atom Count:16
Complexity:194

Purity/Quality:

98%min ^*data from raw suppliers

1-[1-(4-fluorobenzyl)piperidin-4-yl]methanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1CN)CC2=CC=C(C=C2)F

Technology Process of [1-(4-Fluorobenzyl)piperidin-4-yl]methylamine

There total 4 articles about [1-(4-Fluorobenzyl)piperidin-4-yl]methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 174561-04-7
1-[(4-fluorophenyl)methyl]-4-(hydroxymethyl)piperidine

: 174561-02-5
4-aminomethyl-1-(p-fluorobenzyl)piperidine

Guidance literature:

Reference yield:

: 380424-12-4
1-(4-fluoro-benzyl)-piperidine-4-carboxylic acid amide

: 174561-02-5
4-aminomethyl-1-(p-fluorobenzyl)piperidine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 75 ℃; Inert atmosphere;
DOI:10.1080/14756366.2019.1699553

Reference yield:

: 459-46-1
4-Fluorobenzyl bromide

: 174561-02-5
4-aminomethyl-1-(p-fluorobenzyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / methanol / 5 h / 85 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 75 °C / Inert atmosphere

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; methanol;
DOI:10.1080/14756366.2019.1699553