Chemical Property of 4-Piperidinecarboxamide
Chemical Property:
- Appearance/Colour:White to light yellow crystalline powder
- Vapor Pressure:0.000553mmHg at 25°C
- Melting Point:145-148 °C(lit.)
- Refractive Index:1.4880 (estimate)
- Boiling Point:311.7 °C at 760 mmHg
- PKA:16.48±0.20(Predicted)
- Flash Point:142.3 °C
- PSA：55.12000
- Density:1.06 g/cm3
- LogP:0.50040
- Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
- Sensitive.:Hygroscopic
- Solubility.:DMSO (Sparingly), Methanol (Slightly)
- Water Solubility.:Soluble in water.
- XLogP3:-1.4
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:1
- Exact Mass:128.094963011
- Heavy Atom Count:9
- Complexity:108
- Purity/Quality:
-
99% *data from raw suppliers
Isonipecotamide *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-37/39-36
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Canonical SMILES:C1CNCCC1C(=O)N
-
Uses
Anesthetic, analgesic, antimicrobial and cooling agent for prevention or treatment of skin irritation. Reactant for synthesis of:? ;Survival motor neuron (SMN) protein modulators1? ;Diaminotriazine hNav1.7 inhibitors2? ;Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase3? ;Orally available naphthyridine protein kinase D inhibitors4? ;Phosphodiesterase 5 inhibitors5Reactant for identification of small molecular inhibitors of importin-β mediated nublear import6 Isonipecotamide is used as a reactant for the preparation of Survival motor neuron (SMN) protein modulators, orally available naphthyridine protein kinase D inhibitors and heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase. It is also used to prepare phosphodiesterase 5 inhibitors. It is also used as a reactant for identification of small molecular inhibitors of importin-beta mediated nuclear import. It is also used as a fluorenylmethyloxycarbonyl - deprotection agent in organic synthesis.
