1-Methylheptylbromomagnesium

Base Information

• Chemical Name: 1-Methylheptylbromomagnesium
• CAS No.: 21127-63-9
• Molecular Formula: C8H17BrMg
• Molecular Weight: 217.432
• Mol file: 21127-63-9.mol

Synonyms:(1-Methyl-heptyl) magnesium bromide;(1-Methylheptyl)magnesium bromide;1-Methylheptylbromomagnesium;1-Methylheptylmagnesium bromide

Chemical Property of 1-Methylheptylbromomagnesium

Chemical Property:

• PSA: 0.00000
• LogP: 4.16010

Purity/Quality:

2-Octylmagnesiumbromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Methylheptylbromomagnesium

There total 1 articles about 1-Methylheptylbromomagnesium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromooctane (557-35-7,60251-57-2) → 1-methylheptylmagnesium bromide (21127-63-9)

Guidance literature:

With magnesium; lithium chloride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/jacs.9b08586

Reference yield: 85.0%

1-methylheptylmagnesium bromide (21127-63-9) → rac-octan-2-ol (4128-31-8,113301-48-7,4128-32-9)

Guidance literature:

With titanium(IV) isopropylate; tert.-butylhydroperoxide; In diethyl ether; at -78 ℃; for 12h;

DOI:10.1016/S0022-328X(00)00596-9

Reference yield:

ethyl 2-iodobenzoate (1829-28-3) + 1-methylheptylmagnesium bromide (21127-63-9) → ethyl 2-octylbenzoate + ethyl 2-(octan-2-yl)benzoate (1126530-03-7)

Guidance literature:

1-methylheptylmagnesium bromide; With zinc(II) chloride; In tetrahydrofuran;

ethyl 2-iodobenzoate; With dichloro bis(acetonitrile) palladium(II); diethyl bicyclo[2.2.1]hept-2,5-diene-2,3-dicarboxylate; In tetrahydrofuran; at 60 ℃; for 2h; Inert atmosphere;

DOI:10.1002/adsc.200800118

upstream raw materials:

2-bromooctane

Downstream raw materials:

4,5-Dimethyl-undecen-(2)

rac-octan-2-ol

ethyl 2-(octan-2-yl)benzoate

Refernces