1829-28-3Relevant articles and documents
Synthesis of E-stilbene azomethines as potent antimicrobial and antioxidant agents
Iqbal, Ahsan,Khan, Zulfiqar Ali,Shahzad, Sohail Anjum,Usman, Muhammad,Khan, Shakeel Ahmad,Fauq, Abdul H.,Bari, Ayesha,Sajid, Muhammad Aamir
, p. 1518 - 1533 (2018)
A series of new extensively conjugated E -stilbene azomethines (5a–5h) were synthesized and screened for their antioxidant and antimicrobial activity. The compounds were tested against bacterial (Escherichia coli, Staphylococcus aureus, Klebsiella pneumon
Synthesis and antiproliferative activity of substituted benzopyranoisoindoles: A new class of cytotoxic compounds
Hadjipavlou, Christiana,Kostakis, Ioannis K.,Pouli, Nicole,Marakos, Panagiotis,Pratsinis, Harris,Kletsas, Dimitris
, p. 4822 - 4825 (2006)
A series of novel aminosubstituted benzopyranoisoindoles possessing structural analogy to an active nitracrine metabolite are reported. The compounds exhibited interesting cytotoxic activity against a panel of cell lines, which was maximized by the presen
Synthesis, modeling studies and evaluation of E-stilbene hydrazides as potent anticancer agents
Iqbal, Ahsan,Khan, Zulfiqar Ali,Shahzad, Sohail Anjum,Ahmad Khan, Shakeel,Raza Naqvi, Syed Ali,Bari, Ayesha,Amjad, Hira,Umar, Muhammad Ihtisham
, p. 271 - 281 (2019)
A group of new thermodynamically more stable E-2-styrylbenzohydrazide derivatives (5a-i) were synthesized via palladium catalyzed Mizoroki-Heck reaction conditions. All synthesized compounds were characterized by UV-visible, FT-IR, 1H NMR, sup
Ynoate-Initiated Selective C-N Esterification of Tertiary Amines under Transition-Metal and Oxidant-Free Conditions
Sun, Feixiang,Feng, Huangdi,Huang, Liliang,Huang, Junhai
supporting information, p. 713 - 717 (2021/01/14)
An efficient and selective method for metal-and oxidant-free deaminated esterification of tertiary amines is presented. In this protocol, ynoates play a key role to activate the Csp 3-N bond through a process of in situ generation of zwitterionic salts. The transformations show that Csp 3-N bond in the zwitterionic species has a lower dissociation energy than Csp 2-N bond, leading to break preferentially and be trapped by carboxylic acids to generate the corresponding products in moderate to good yield.