2-aMino-6-(((benzyloxy)carbonyl)aMino)hexanoic acid

Base Information

• Chemical Name: 2-aMino-6-(((benzyloxy)carbonyl)aMino)hexanoic acid
• CAS No.: 32302-83-3
• Molecular Formula: C14H20N2O4
• Molecular Weight: 280.324
• Mol file: 32302-83-3.mol

Synonyms:N6-Benzyloxycarbonyl-DL-lysin;Nε-Benzyloxycarbonyllysin;N-ε-benzyloxycarbonyl lysine;2-amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid;(R,S)-6-N-benzyloxycarbonyl-DL-lysine;N6-benzyloxycarbonyl-DL-lysine;

Chemical Property of 2-aMino-6-(((benzyloxy)carbonyl)aMino)hexanoic acid

Chemical Property:

• PSA: 101.65000
• LogP: 2.58620

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-6-(((benzyloxy)carbonyl)amino)hexanoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-aMino-6-(((benzyloxy)carbonyl)aMino)hexanoic acid

There total 11 articles about 2-aMino-6-(((benzyloxy)carbonyl)aMino)hexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

D-lysine (923-27-3,3506-25-0) + benzyl chloroformate (501-53-1,94274-21-2) → (R)-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid (34404-32-5,1155-64-2,32302-83-3,57705-97-2,67178-46-5,25931-47-9)

Guidance literature:

D-lysine; With copper(II) sulfate; sodium hydroxide; In water; at 20 ℃; for 5h;

benzyl chloroformate; With ethylenediaminetetraacetic acid; at 20 ℃; for 3h;

DOI:10.3184/174751915X14326563172262

Reference yield:

N-ε-benzyloxycarbonyl lysine (32302-83-3,57705-97-2,67178-46-5,25931-47-9) → (R)-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid (34404-32-5,1155-64-2,32302-83-3,57705-97-2,67178-46-5,25931-47-9)

Guidance literature:

With L-amino acid oxide ase-substance from crotalus adamanteus;

DOI:10.1021/ja01537a052

Reference yield:

For-D-Lys(-Z)-OH (67427-40-1) → (R)-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid (34404-32-5,1155-64-2,32302-83-3,57705-97-2,67178-46-5,25931-47-9)

Guidance literature:

With toluene-4-sulfonic acid; In 1,4-dioxane;

DOI:10.1246/bcsj.51.1899

upstream raw materials:

2,6-diaminocaproic acid

N-ε-benzyloxycarbonyl lysine

For-D-Lys(-Z)-OH

D-lysine hydrochloride

Downstream raw materials:

D-lysine

(R)-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoic acid

N⁶-benzyloxycarbonyl-N²-propionyl-lysine

N⁶-benzyloxycarbonyl-N²-butyryl-lysine