3,5-DIOXO-2-[3-(TRIFLUOROMETHYL)PHENYL]-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE-6-CARBONITRILE

Base Information

• Chemical Name: 3,5-DIOXO-2-[3-(TRIFLUOROMETHYL)PHENYL]-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE-6-CARBONITRILE
• CAS No.: 121065-97-2
• Molecular Formula: C11H5F3N4O2
• Molecular Weight: 282.182
• Hs Code.: 2933698090
• Mol file: 121065-97-2.mol

Synonyms:3,5-DIOXO-2,3,4,5-TETRAHYDRO-2-[(3-TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZINE-6-CARBONITRILE;3,5-DIOXO-2-[3-(TRIFLUOROMETHYL)PHENYL]-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE-6-CARBONITRILE;6-CYANO-2,3,4,5-TETRAHYDRO-2-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZIN-3,5-DIONE;3,5-Dioxo-2,3,4,5-tetrahydro-2-[3-(trifluoromethyl)phenyl]-1,2,4-triazine-6-carbonitrile 97%;3,5-Dioxo-2,3,4,5-tetrahydro-2-[3-(trifluoromethyl)phenyl]-1,2,4-triazine-6-carbonitrile97%

Chemical Property of 3,5-DIOXO-2-[3-(TRIFLUOROMETHYL)PHENYL]-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE-6-CARBONITRILE

Chemical Property:

• Melting Point: 173-175°C
• PSA: 91.54000
• LogP: 0.81128

Purity/Quality:

97% ^*data from raw suppliers

3,5-Dioxo-2,3,4,5-tetrahydro-2-[3-(trifluoromethyl)phenyl]-1,2,4-triazine-6-carbonitrile 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 3,5-DIOXO-2-[3-(TRIFLUOROMETHYL)PHENYL]-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE-6-CARBONITRILE

There total 3 articles about 3,5-DIOXO-2-[3-(TRIFLUOROMETHYL)PHENYL]-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE-6-CARBONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.01%

ethyl (Z)-(2-cyano-2-(2-(3-(trifluoromethyl)phenyl)hydrazono)acetyl)carbamate → 3,5-dioxo-2-(3-(trifluoromethyl)phenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile (121065-97-2)

Guidance literature:

With sodium acetate; acetic acid; for 2h; Reflux;

DOI:10.1016/j.ejmech.2016.04.062

Reference yield:

C13H11F3N4O3 (118806-30-7) → 3,5-dioxo-2-(3-(trifluoromethyl)phenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile (121065-97-2)

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; at 140 ℃;

DOI:10.1016/j.bmcl.2010.01.116

Reference yield:

3-trifluoromethylaniline (98-16-8) → 3,5-dioxo-2-(3-(trifluoromethyl)phenyl)-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile (121065-97-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium nitrite; hydrogenchloride / water / 0.5 h / 0 °C

1.2: 2 h / 0 °C

2.1: acetic acid; sodium acetate / 2 h / Reflux

With hydrogenchloride; sodium acetate; acetic acid; sodium nitrite; In water;

DOI:10.1016/j.ejmech.2016.04.062

upstream raw materials:

C₁₃H₁₁F₃N₄O₃

3-trifluoromethylaniline

Downstream raw materials:

C₁₈H₁₈F₃N₅O₂

C₁₉H₂₀F₃N₅O₂

C₁₅H₁₃F₃N₄O₂

4-methyl-3,5-dioxo-2-(3-(trifluoromethyl)phenyl)-2,3,4,5-tetrahydro-1,2, 4-triazine-6-carbonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 121065-97-2 3,5-DIOXO-2-[3-(TRIFLUOROMETHYL)PHENYL]-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZINE-6-CARBONITRILE

Send

Send

Metric Ton KG G Pound L ML

Send

Send