2-(BenzylaMino)ethyl hydrogen sulfate

Base Information

• Chemical Name: 2-(BenzylaMino)ethyl hydrogen sulfate
• CAS No.: 2133-07-5
• Molecular Formula: C9H13NO4S
• Molecular Weight: 231.273
• Hs Code.: 2922199090
• Mol file: 2133-07-5.mol

Synonyms:2-(BenzylaMino)ethyl hydrogen sulfate;Sulfuric acid mono-(2-benzylamino-ethyl) ester

Chemical Property of 2-(BenzylaMino)ethyl hydrogen sulfate

Chemical Property:

• Melting Point: 230-231 °C
• PKA: -3.86±0.18(Predicted)
• PSA: 84.01000
• Density: 1.340±0.06 g/cm3(Predicted)
• LogP: 2.06730
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-(Benzylamino)ethylhydrogensulfate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(BenzylaMino)ethyl hydrogen sulfate

There total 2 articles about 2-(BenzylaMino)ethyl hydrogen sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-Benzylethanolamine (104-63-2) → 2-(benzylamino)ethyl hydrogen sulfate (2133-07-5)

Guidance literature:

With sulfuric acid; In toluene; at 35 ℃; Inert atmosphere; Dean-Stark; Reflux; Large scale;

DOI:10.1021/acs.oprd.5b00014

Reference yield:

ethyleneglycol sulfate (1072-53-3) + benzylamine (100-46-9) → 2-(benzylamino)ethyl hydrogen sulfate (2133-07-5)

Guidance literature:

In dichloromethane;

Reference yield: 65.0%

2-(benzylamino)ethyl hydrogen sulfate (2133-07-5) + (S)-benzyl glycidyl ether (2930-05-4,14618-80-5,89616-40-0,16495-13-9) → (2S)-4-(phenylmethyl)-2-{[(phenylmethyl)oxy]methyl}morpholine (205242-66-6)

Guidance literature:

2-(benzylamino)ethyl hydrogen sulfate; (S)-benzyl glycidyl ether; With sodium hydroxide; In methanol; water; at 0 - 40 ℃; for 3.33333h;

In methanol; water; toluene; at 0 - 65 ℃; for 3.16667h;

upstream raw materials:

ethyleneglycol sulfate

benzylamine

N-Benzylethanolamine

Downstream raw materials:

3-benzyl-1,3-thiazolidine-2-thione

(2S)-4-(phenylmethyl)-2-{[(phenylmethyl)oxy]methyl}morpholine

(S)-1-benzyl-2-phenoxymethylmorpholine

1-benzylaziridine