O-Bis(2-aminoethoxy)benzene

Base Information

• Chemical Name: O-Bis(2-aminoethoxy)benzene
• CAS No.: 42988-85-2
• Molecular Formula: C10H18Cl2N2O2
• Molecular Weight: 196.249
• Hs Code.: 2922299090
• DSSTox Substance ID: DTXSID60366033
• Nikkaji Number: J2.035.465H
• Wikidata: Q82151086
• ChEMBL ID: CHEMBL1622514
• Mol file: 42988-85-2.mol

Synonyms:42988-85-2;O-Bis(2-aminoethoxy)benzene;2-[2-(2-aminoethoxy)phenoxy]ethanamine;2,2'-(1,2-Phenylenebis(oxy))diethanamine;1,2-Bis(2-aminoethoxy)benzene;2,2'-[benzene-1,2-diylbis(oxy)]diethanamine;CBDivE_001478;SCHEMBL8834938;CHEMBL1622514;DTXSID60366033;1,2-di(2-amino-ethoxy)-benzene;BBL008247;STK520577;AKOS002313590;VS-01865;{2-[2-(2-aminoethoxy)phenoxy]ethyl}amine;2-[2-(2-aminoethoxy)phenoxy]-1-ethanamine;2-[2-(2-aminoethoxy)phenoxy]ethan-1-amine;CS-0188320;EU-0067152;FT-0662492;E76293;2,2'-[1,2-Phenylenebis(oxy)]di(ethan-1-amine);SR-01000391866;SR-01000391866-1

Chemical Property of O-Bis(2-aminoethoxy)benzene

Chemical Property:

• PSA: 70.50000
• LogP: 3.36620
• Solubility.: Dichloromethane
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 196.121177757
• Heavy Atom Count: 14
• Complexity: 128

Purity/Quality:

99% ^*data from raw suppliers

O-Bis(2-aminoethoxy)benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)OCCN)OCCN
• Uses: O-Bis(2-aMinoethoxy)benzene can be used in the preparation of diazacoronands, useful due to their binding properties.

Technology Process of O-Bis(2-aminoethoxy)benzene

There total 4 articles about O-Bis(2-aminoethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

di-tert-butyl-([1,2-phenylenebis(oxy)]bis[ethane-2,1-diyl])dicarbamate → 2,2’-[1,2-phenylenebis(oxy)]diethanamine (42988-85-2)

Guidance literature:

With acetyl chloride; In methanol; at 0 - 20 ℃; for 24h;

DOI:10.1021/acs.inorgchem.0c01053

Reference yield:

N,N'-(2,2'-o-phenylenedioxy-diethyl)-bis-phthalimide (72814-11-0) → 2,2’-[1,2-phenylenebis(oxy)]diethanamine (42988-85-2)

Guidance literature:

With hydrazine hydrate; In ethanol;

DOI:10.1039/P19790002193

Reference yield:

Brenzcatechin-bis-(2-azidoethylether) (72814-03-0) → 2,2’-[1,2-phenylenebis(oxy)]diethanamine (42988-85-2)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1039/P19790002193

upstream raw materials:

N,N'-(2,2'-o-phenylenedioxy-diethyl)-bis-phthalimide

Brenzcatechin-bis-(2-azidoethylether)

bis(o-phenylene)glycol ditosylate

Downstream raw materials:

N,N'-(2,2'-o-phenylenedioxy-diethyl)-bis-carbamic acid dibenzyl ester

26-benzyloxy-2,8,15,21-tetraoxa-5,18-diaza-tricyclo[20.3.1.0^9,14]hexacosa-1⁽²⁵⁾,9⁽¹⁴⁾,10,12,22⁽²⁶⁾,23-hexaene-4,19-dione

{2-[2-(2-Ethoxycarbonylamino-ethoxy)-phenoxy]-ethyl}-carbamic acid ethyl ester