Methyl 3-Methanesulfonyl-4-Methylbenzoate

Base Information

• Chemical Name: Methyl 3-Methanesulfonyl-4-Methylbenzoate
• CAS No.: 906816-32-8
• Molecular Formula: C10H12O4S
• Molecular Weight: 228.269
• Hs Code.: 2916399090
• Mol file: 906816-32-8.mol

Synonyms:Methyl 3-Methanesulfonyl-4-Methylbenzoate;Methyl 4-Methyl-3-(Methylsulfonyl)benzoate

Chemical Property of Methyl 3-Methanesulfonyl-4-Methylbenzoate

Chemical Property:

• PSA: 68.82000
• LogP: 2.26590
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Methyl4-Methyl-3-(methylsulfonyl)benzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-Methanesulfonyl-4-Methylbenzoate

There total 3 articles about Methyl 3-Methanesulfonyl-4-Methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-3-sulfinobenzoic acid + methyl iodide (74-88-4) → methyl 4-methyl-3-methylsulfonylbenzoate (906816-32-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 4h;

Reference yield:

3-(chlorosulfonyl)-4-methylbenzoic acid (2548-29-0) → methyl 4-methyl-3-methylsulfonylbenzoate (906816-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide; sodium sulfite / water / pH 10

1.2: pH 2

2.1: potassium carbonate / N,N-dimethyl-formamide / 4 h

With potassium carbonate; sodium hydroxide; sodium sulfite; In water; N,N-dimethyl-formamide;

Reference yield:

p-Toluic acid (99-94-5) → methyl 4-methyl-3-methylsulfonylbenzoate (906816-32-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: chlorosulfonic acid / 0 - 130 °C

1.2: 0.17 h / 0 °C

2.1: sodium hydroxide; sodium sulfite / water / pH 10

2.2: pH 2

3.1: potassium carbonate / N,N-dimethyl-formamide / 4 h

With chlorosulfonic acid; potassium carbonate; sodium hydroxide; sodium sulfite; In water; N,N-dimethyl-formamide;

upstream raw materials:

methyl iodide

3-(chlorosulfonyl)-4-methylbenzoic acid

p-Toluic acid

Downstream raw materials:

4-methyl-3-methylsulfonylbenzoic acid

4-(1-azidomethyl)-1-methyl-2-(methylsulfonyl)benzene

(4-methyl-3-(methylsulfonyl)phenyl)methanamine

[3-(methanesulfonyl)-4-methylphenyl]methanol

Refernces