6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

Base Information

Chemical Name:6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one
CAS No.:307548-94-3
Molecular Formula:C₁₆H₁₆O₄
Molecular Weight:272.301
Hs Code.:
DSSTox Substance ID:DTXSID20397328
Pharos Ligand ID:8417XWLY8GS1
ChEMBL ID:CHEMBL488076
Mol file:307548-94-3.mol

Synonyms:307548-94-3;6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one;CHEMBRDG-BB 6159766;6-methyl-7-(2-oxopropoxy)-2,3-dihydro-1H-cyclopenta[c]chromen-4-one;CHEMBL488076;7-Acetonyloxy-3,4-cyclopentene-8-methylcoumarin;6-METHYL-7-(2-OXOPROPOXY)-2,3-DIHYDROCYCLOPENTA(C)CHROMEN-4(1H)-ONE;CBMicro_001748;D00OQL;DTXSID20397328;SMSF0015818;BDBM50246264;MFCD01845284;STK829219;AKOS001021363;CB03533;BS-35930;PD183066;BIM-0001876.P001;EN300-24107510;SR-01000229477;SR-01000229477-1;Z56795414;6-methyl-7-(2-oxopropoxy)-1,2,3,4-tetrahydrocyclopenta[c]chromen-4-one;6-METHYL-7-(2-OXOPROPOXY)-1H,2H,3H,4H-CYCLOPENTA[C]CHROMEN-4-ONE

Suppliers and Price of 6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

Chemical Property:

Vapor Pressure:8.59E-09mmHg at 25°C
Boiling Point:464.1°C at 760 mmHg
Flash Point:208.1°C
Density:1.26g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:272.10485899
Heavy Atom Count:20
Complexity:465

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC2=C1OC(=O)C3=C2CCC3)OCC(=O)C

Technology Process of 6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

There total 4 articles about 6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 55047-28-4
7-hydroxy-6-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

: 598-31-2
1-bromoacetone

: 307548-94-3
6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

Guidance literature:: With potassium carbonate; In acetone; at 50 - 56 ℃;
DOI:10.1023/A:1020423826071

Reference yield: 76.0%

: 55047-28-4
7-hydroxy-6-methyl-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

: 78-95-5
chloroacetone

: 307548-94-3
6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

Guidance literature:: With potassium carbonate; In acetone; for 24h; Reflux;
DOI:10.1021/jm800656v

Reference yield:

: 608-25-3
2-methylbenzene-1,3-diol

: 307548-94-3
6-methyl-7-(2-oxopropoxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / H₂SO₄ / ethanol / 0 - 20 °C

2: 92 percent / K₂CO₃ / acetone / 50 - 56 °C

With sulfuric acid; potassium carbonate; In ethanol; acetone; 1: Pechmann condensation / 2: Williamson reaction;
DOI:10.1023/A:1020423826071