ESTRONE-2,4-D2

Base Information

Chemical Name:ESTRONE-2,4-D2
CAS No.:350820-16-5
Molecular Formula:C₁₈H₂₂O₂
Molecular Weight:277.316
Hs Code.:
Mol file:350820-16-5.mol

Synonyms:ESTRONE-2,4-D2

Suppliers and Price of ESTRONE-2,4-D2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
Estrone-2,4-d2
25 mg
$ 290.00

Cayman Chemical
Estrone-d2 ≥98%
1mg
$ 55.00

Cayman Chemical
Estrone-d2 ≥98%
500μg
$ 29.00

American Custom Chemicals Corporation
ESTRONE-2,4-D2 95.00%
5MG
$ 495.33

AK Scientific
(8R,9S,13S,14S)-2,4-Dideuterio-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
1mg
$ 174.00

Total 3 raw suppliers

Chemical Property of ESTRONE-2,4-D2

Chemical Property:

PSA：37.30000
LogP:3.81740
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly, Sonicated), Ethanol (Slightly, Sonicated) Methanol (Slight

Purity/Quality:

NLT 98% ^*data from raw suppliers

Estrone-2,4-d2 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Estrone-d2 is intended for use as an internal standard for the quantification of estrone (Item Nos. ISO60165 | 10006485) by GC- or LC-MS. Estrone is one of the three naturally occurring estrogens, the others being estradiol (Item Nos. ISO60155 | 10006315) and estriol (Item Nos. ISO60164 | 10006484). Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women. The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.
Uses Estrone-2,4-d2 (CAS# 350820-16-5) is a useful isotopically labeled research compound. It could potentially be useful as a wetland substrate for the removal of pharmaceutical and personal care products from contaminated water.

Technology Process of ESTRONE-2,4-D2

There total 15 articles about ESTRONE-2,4-D2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 53-16-7
Estrone

: 53866-34-5,350820-16-5
estrone-2,4,16,16-d₄

Guidance literature:: Estrone; With trifluoroacetic acid-d₁; for 0.166667h; heating in a microwave oven;

With ethanol;
DOI:10.1016/S0040-4039(02)00509-9

Reference yield: 81.0%

: 53-16-7
Estrone

: 350820-16-5
1,2,4,16α,16β-pentadeuterioestrone

Guidance literature:: With trifluoroacetic acid-d₁; water-d2; for 20h; regioselective reaction; Reflux;
DOI:10.1016/j.steroids.2014.08.018

Reference yield: 78.0%

: 21003-02-1
3-hydroxy-2-(1',1'-dimethylethyl)estra-1,3,5⁽¹⁰⁾-trien-17-one

: 350820-16-5
1,2,4,16α,16β-pentadeuterioestrone

Guidance literature:: With water-d2; magnesium sulfate; trifluoroacetic anhydride; at 0 ℃; for 20.5h; regioselective reaction; Reflux;
DOI:10.1016/j.steroids.2014.08.018