N,N'-Bis(2-mercaptobenzoyl)hydrazide

Base Information

Chemical Name:N,N'-Bis(2-mercaptobenzoyl)hydrazide
CAS No.:292615-41-9
Molecular Formula:C₁₄H₁₂N₂O₂S₂
Molecular Weight:304.393
Hs Code.:
NSC Number:704784
DSSTox Substance ID:DTXSID90327935
Nikkaji Number:J1.094.608E
Wikidata:Q82090085
ChEMBL ID:CHEMBL157428
Mol file:292615-41-9.mol

Synonyms:N,N'-Bis(2-mercaptobenzoyl)hydrazide;292615-41-9;1217678-56-2;2-sulfanyl-n'-(2-sulfanylbenzoyl)benzohydrazide;CHEMBL157428;BIS(THIOSALICYL)HYDRAZIDE;NSC704784;Benzoic acid, 2-mercapto-, 2-(2-mercaptobenzoyl)hydrazide;(+/-)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane Disulfide;2-Sulfanyl-n/'-(2-sulfanylbenzoyl)benzohydrazide;SCHEMBL7885471;DTXSID90327935;BDBM50121971;NSC 691995;NSC-704784;L-17;NCI60_037411;FT-0663323;FT-0663324;N,N'-BIS-(2-MERCAPTOBENZOYL)HYDRAZIDE;J-017455;2-Mercapto-benzoic Acid 2-(2-Mercaptobenzoyl)hydrazide;2-Mercapto-benzoic acid N''-(2-mercapto-benzoyl)-hydrazide;N,N inverted exclamation mark -Bis(2-mercaptobenzoyl)hydrazide

Suppliers and Price of N,N'-Bis(2-mercaptobenzoyl)hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N,N’-Bis(2-mercaptobenzoyl)hydrazide
100mg
$ 1135.00

TRC
N,N’-Bis(2-mercaptobenzoyl)hydrazide
10mg
$ 145.00

Biosynth Carbosynth
N,N'-Bis(2-mercaptobenzoyl)hydrazide
5 g
$ 1201.20

Biosynth Carbosynth
N,N'-Bis(2-mercaptobenzoyl)hydrazide
250 mg
$ 112.50

Biosynth Carbosynth
N,N'-Bis(2-mercaptobenzoyl)hydrazide
2 g
$ 660.70

Biosynth Carbosynth
N,N'-Bis(2-mercaptobenzoyl)hydrazide
1 g
$ 363.40

Biosynth Carbosynth
N,N'-Bis(2-mercaptobenzoyl)hydrazide
500 mg
$ 200.00

Total 2 raw suppliers

Chemical Property of N,N'-Bis(2-mercaptobenzoyl)hydrazide

Chemical Property:

Melting Point:170°C dec.
Boiling Point:596.7oC at 760 mmHg
Flash Point:314.7oC
PSA：142.78000
LogP:3.48840
XLogP3:2.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:304.03401998
Heavy Atom Count:20
Complexity:331

Purity/Quality:

97% ^*data from raw suppliers

N,N’-Bis(2-mercaptobenzoyl)hydrazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)NNC(=O)C2=CC=CC=C2S)S
Uses A selective inhibitor of HIV-1 integrase. Has no other effect on other retroviral targets, including reverse transcriptase, protease, and virus attachement, and exhibits no detectable activity against human topoisomerases I and II at concentrations that effectively inhibit integrase.

Technology Process of N,N'-Bis(2-mercaptobenzoyl)hydrazide

There total 3 articles about N,N'-Bis(2-mercaptobenzoyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 292615-39-5
C₂₈H₂₂N₄O₄S₄

: 292615-41-9
2-mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hydrazide

Guidance literature:: With water; triethylphosphine; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1021/jm0201417

Reference yield:

: 19602-82-5
2,2'-dithiodibenzoic acid dichloride

: 292615-41-9
2-mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 2.50 g / pyridine / toluene; dimethylformamide / 36 h / 20 °C

2: 80 percent / triethylphosphine; water / tetrahydrofuran / 0.5 h / 20 °C

With pyridine; water; triethylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm0201417

Reference yield:

: 119-80-2
2,2'-dithiobenzoic acid

: 292615-41-9
2-mercapto-benzoic acid N'-(2-mercapto-benzoyl)-hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / benzene / 3 h / Heating

2: 2.50 g / pyridine / toluene; dimethylformamide / 36 h / 20 °C

3: 80 percent / triethylphosphine; water / tetrahydrofuran / 0.5 h / 20 °C

With pyridine; thionyl chloride; water; triethylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1021/jm0201417