D-threo-Ritalinic Acid

Base Information Edit

Chemical Name:D-threo-Ritalinic Acid
CAS No.:54631-24-2
Deprecated CAS:56552-74-0
Molecular Formula:C₁₃H₁₇NO₂
Molecular Weight:219.283
Hs Code.:
UNII:2MNC5Y0IMU,GT4165RS9H
Nikkaji Number:J1.615.276E
Wikidata:Q106634517
Mol file:54631-24-2.mol

Synonyms:alpha-phenyl-2-piperidineacetic acid;ritalinic acid;ritalinic acid, (R*,R*)-(+-)-isomer

Suppliers and Price of D-threo-Ritalinic Acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DL-THREO-RITALINIC ACID 95.00%
5MG
$ 501.47

Total 24 raw suppliers

Chemical Property of D-threo-Ritalinic Acid Edit

Chemical Property:

Boiling Point:367.7±17.0 °C(Predicted)
PKA:3.50±0.10(Predicted)
PSA：49.33000
Density:1.138±0.06 g/cm3(Predicted)
LogP:2.32570
XLogP3:-2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:219.125928785
Heavy Atom Count:16
Complexity:236

Purity/Quality:

99%, ^*data from raw suppliers

DL-THREO-RITALINIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCNC(C1)C(C2=CC=CC=C2)C(=O)O
Isomeric SMILES:C1CCN[C@H](C1)[C@@H](C2=CC=CC=C2)C(=O)O
Uses A metabolite

Technology Process of D-threo-Ritalinic Acid

There total 17 articles about D-threo-Ritalinic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.6%

: threo-α-phenyl-α-(2-piperidyl)acetamide

: 19395-41-6,1076192-92-1,54631-24-2,744954-37-8
Ritalinic acid

Guidance literature:: With hydrogenchloride; water; Reflux;

Reference yield: 88.6%

: threo-α-phenyl-α-(2-piperidyl)acetamide

: 1076192-92-1,54631-24-2,744954-37-8
threo-ritalinic acid

Guidance literature:: threo-α-phenyl-α-(2-piperidyl)acetamide; With hydrogenchloride; water; for 2 - 6h; Reflux;

With sodium hydroxide; In water; pH=6 - 7;

Reference yield: 40.0%

: 298-59-9,19262-68-1,23644-60-2,23655-65-4,29419-95-2,29419-96-3,29419-97-4,56502-30-8
methylphenidate hydrochloride

: 1076192-92-1,54631-24-2,744954-37-8
2-phenyl-2-(piperidin-2-yl)acetic acid

Guidance literature:: With water; potassium hydroxide; In ethanol; at 20 ℃; for 19.3h; pH=5; Reagent/catalyst; Temperature;
DOI:10.1107/S010827011302595X