DiMethyl piperidine-3,5-dicarboxylate

Base Information

• Chemical Name: DiMethyl piperidine-3,5-dicarboxylate
• CAS No.: 54732-79-5
• Molecular Formula: C9H15NO4
• Molecular Weight: 201.2197
• Hs Code.: 2933399990
• Mol file: 54732-79-5.mol

Synonyms:DiMethyl piperidine-3,5-dicarboxylate;diMethyl piperidine-3,5-dicarboxylate acetate

Chemical Property of DiMethyl piperidine-3,5-dicarboxylate

Chemical Property:

• PSA: 64.63000
• LogP: -0.11310

Purity/Quality:

97% ^*data from raw suppliers

DimethylPiperidine-3,5-dicarboxylateAcetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DiMethyl piperidine-3,5-dicarboxylate

There total 5 articles about DiMethyl piperidine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

dimethyl pyridine-3,5-dicarboxylate (4591-55-3) → dimethyl piperidine-3,5-dicarboxylate (54732-79-5)

Guidance literature:

With Adam’s catalyst; hydrogen; acetic acid; for 216h; under 2585.81 Torr;

Reference yield: 88.6%

dimethyl pyridine-3,5-dicarboxylate hydrochloride → dimethyl piperidine-3,5-dicarboxylate (54732-79-5)

Guidance literature:

dimethyl pyridine-3,5-dicarboxylate hydrochloride; With hydrogen; platinum(IV) oxide; In acetic acid; at 23 ℃; for 36h; under 2327.23 Torr;

With sodium hydrogencarbonate;

Reference yield:

3,5-Pyridinedicarboxylic acid (499-81-0) → dimethyl piperidine-3,5-dicarboxylate (54732-79-5)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂

2: H₂ / PtO₂ / acetic acid / 12 h / 2585.7 Torr

With thionyl chloride; hydrogen; platinum(IV) oxide; In acetic acid;

DOI:10.1016/S0040-4039(00)60715-3

upstream raw materials:

3,5-Pyridinedicarboxylic acid

dimethyl pyridine-3,5-dicarboxylate

Downstream raw materials:

(3R,5S)-1-(tert-butoxycarbonyl)piperidine-3,5-dicarboxylic acid