O(1),O(3)-BIS(CARBOXYMETHYL)-O(2),O(4)-DIMETHYL-P-T-BUTYLCALIX(4)ARENE

Base Information

• Chemical Name: O(1),O(3)-BIS(CARBOXYMETHYL)-O(2),O(4)-DIMETHYL-P-T-BUTYLCALIX(4)ARENE
• CAS No.: 136157-98-7
• Molecular Formula: C₅₀H₆₄O₈
• Molecular Weight: 793.053
• Mol file: 136157-98-7.mol

Synonyms:O(1),O(3)-BIS(CARBOXYMETHYL)-O(2),O(4)-DIMETHYL-P-T-BUTYLCALIX(4)ARENE;O(1),O(3)-Bis(carboxymethyl)-O(2),O(4)-dimethyl-p-tert-butylcalix[4]arene;

Chemical Property of O(1),O(3)-BIS(CARBOXYMETHYL)-O(2),O(4)-DIMETHYL-P-T-BUTYLCALIX(4)ARENE

Chemical Property:

• Vapor Pressure: 2.49E-30mmHg at 25°C
• Melting Point: 250-252°C
• Boiling Point: 844.9°C at 760 mmHg
• Flash Point: 238.2°C
• PSA: 111.52000
• Density: 1.105g/cm³
• LogP: 10.49720

Purity/Quality:

99% ^*data from raw suppliers

O(1),O(3)-BIS(CARBOXYMETHYL)-O(2),O(4)-DIMETHYL-P-T-BUTYLCALIX(4)ARENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of O(1),O(3)-BIS(CARBOXYMETHYL)-O(2),O(4)-DIMETHYL-P-T-BUTYLCALIX(4)ARENE

There total 4 articles about O(1),O(3)-BIS(CARBOXYMETHYL)-O(2),O(4)-DIMETHYL-P-T-BUTYLCALIX(4)ARENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,2'-<<5,11,17,23-Tetrakis(1,1-dimethylethyl)-26,28-dimethoxypentacyclo<19.3.1.13,7.19,13.115,19>octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-25,27-diyl>bis(oxy)>bis(acetic acid), dimethyl ester (136157-97-6) → 5,11,17,23-tetra-tert-butyl-25,27-dicarboxymethoxy-26,28-dimethoxycalix[4]arene (136157-98-7)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 4h; Heating;

Reference yield: 98.0%

25,27-Dimethoxy-26,28-bis(ethoxycarbonylmethoxy)-5,11,17,23-tetra-t-butylcalix<4>arene (149775-71-3) → 5,11,17,23-tetra-tert-butyl-25,27-dicarboxymethoxy-26,28-dimethoxycalix[4]arene (136157-98-7)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 24h; Inert atmosphere; Reflux;

DOI:10.1007/s10847-015-0574-z

Reference yield:

24,26-dimethoxy-25,27-dihydroxy-5,11,17,23-tetra(4-tert-butyl)calix[4]arene (122406-45-5) → 5,11,17,23-tetra-tert-butyl-25,27-dicarboxymethoxy-26,28-dimethoxycalix[4]arene (136157-98-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / K₂CO₃ / acetone / 48 h / Ambient temperature

2: 99 percent / NaOH / ethanol; H₂O / 4 h / Heating

With sodium hydroxide; potassium carbonate; In ethanol; water; acetone;

upstream raw materials:

2,2'-<<5,11,17,23-Tetrakis(1,1-dimethylethyl)-26,28-dimethoxypentacyclo<19.3.1.1^3,7.1^9,13.1^15,19>octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-25,27-diyl>bis(oxy)>bis(acetic acid), dimethyl ester

24,26-dimethoxy-25,27-dihydroxy-5,11,17,23-tetra(4-tert-butyl)calix[4]arene

25,27-Dimethoxy-26,28-bis(ethoxycarbonylmethoxy)-5,11,17,23-tetra-t-butylcalix<4>arene

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene