1,3-DIMETHOXY-4-TERT-BUTYLCALIX(4)ARENE

Base Information

• Chemical Name: 1,3-DIMETHOXY-4-TERT-BUTYLCALIX(4)ARENE
• CAS No.: 122406-45-5
• Molecular Formula: C46H60 O4
• Molecular Weight: 676.98
• Hs Code.: 29071990
• Mol file: 122406-45-5.mol

Synonyms:1,3-Dimethoxy-p-tert-butylcalix[4]arene;25,27-Dimethoxy-5,11,17,23-tetra-tert-butylcalix[4]arene;5,11,17,23-Tetra-tert-butyl-25,27-dimethoxy-26,28-dihydroxycalix[4]arene;5,11,17,23-Tetra-tert-butyl-26,28-dimethoxycalix[4]arene-25,27-diol

Chemical Property of 1,3-DIMETHOXY-4-TERT-BUTYLCALIX(4)ARENE

Chemical Property:

• Vapor Pressure: 5.43E-21mmHg at 25°C
• Refractive Index: 1.557
• Boiling Point: 712.8°Cat760mmHg
• Flash Point: 384.9°C
• PSA: 58.92000
• Density: 1.051g/cm³
• LogP: 10.98160

Purity/Quality:

98%min ^*data from raw suppliers

1,3-DIMETHOXY-4-TERT-BUTYLCALIX[4]ARENE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-DIMETHOXY-4-TERT-BUTYLCALIX(4)ARENE

There total 10 articles about 1,3-DIMETHOXY-4-TERT-BUTYLCALIX(4)ARENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) + methyl iodide (74-88-4) → 24,26-dimethoxy-25,27-dihydroxy-5,11,17,23-tetra(4-tert-butyl)calix[4]arene (122406-45-5)

Guidance literature:

With potassium hydroxide; In chloroform; water; at 20 ℃; for 20h;

DOI:10.1080/00397919908086010

Reference yield: 89.0%

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) + methyl p-toluene sulfonate (80-48-8) → 24,26-dimethoxy-25,27-dihydroxy-5,11,17,23-tetra(4-tert-butyl)calix[4]arene (122406-45-5)

Guidance literature:

With potassium carbonate; In acetonitrile; for 24h; Heating;

Reference yield: 86.0%

26,28-dimethoxycalix[4]arene-25,27-diol (125065-61-4,142433-64-5,1021694-88-1) + methyl iodide (74-88-4) → 24,26-dimethoxy-25,27-dihydroxy-5,11,17,23-tetra(4-tert-butyl)calix[4]arene (122406-45-5)

Guidance literature:

With potassium carbonate; In acetone; Heating;

DOI:10.1016/S0040-4020(97)10078-3

upstream raw materials:

diazomethane

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene

5,11,17,23-tetra(tert-butyl)-25,26,27,28-tetramethoxycalix[4]arene

methyl p-toluene sulfonate

Downstream raw materials:

C₆₂H₇₄N₂O₁₀

5,11,17,23-tetrakis-tert-butyl-25,27-dimethoxy-26-benzoylaminocarbonyl-28-hydroxycalix[4]arene

5,11,17,23-tetrakis-tert-butyl-25,27-dimethoxy-26-trichloroacetylaminocarbonyl-28-hydroxycalix[4]arene

(t-butylcalix[4]arene-4H)(Me₂)(C₆H₃(CN)2)2

Refernces

• 1、 Gruner, Margit,Fischer, Conrad,Gruber, Tobias,Weber, Edwin. "Influence of laterally attached alkyl groups on the conformational behaviour of a basic calix[4]arene: Combined NMR, molecular mechanics and X-ray study". . p. 256 - 266. Retrieved 2010.
• 2、 Sutariya, Pinkesh G.,Soni, Heni,Gandhi, Sahaj A.,Pandya, Alok. "Turn on fluorescence strip based sensor for recognition of Sr2+ and CN? via lowerrim substituted calix[4]arene and its computational investigation". . . Retrieved 2020.
• 3、 O'Malley, Shane,Schazmann, Benjamin,Diamond, Dermot,Nolan, Kieran. "Preparation and sensor evaluation of a Pacman phthalocyanine". . p. 9003 - 9007. Retrieved 2007.
• 4、 Chawla,Pant,Srivastava, Bindu. "Regioselective ipso formylation of p-tert-butylcalix[4]arene". . p. 7259 - 7262. Retrieved 2005.
• 5、 Aoki, Izuo,Kawabata, Hirosuke,Nakashima, Kazuaki,Shinkai, Seiji. "Fluorescent Calixarene which responds to Solvent Polarity and Metal Ions". . p. 1771 - 1773. Retrieved 1991.
• 6、 Zhao, Bing,Feng, Ya-Qing,Zhang, Sha-Sha. "Novel synthesis and characterization of 1,3-bis(2-dihydrothiazolyl) thiaalkoxy-p-tert-butylcalix[4]arenes". . p. 3479 - 3484. Retrieved 2007.
• 7、 Pitarch, Miguel,Browne, Julie K.,McKervey, M. Anthony. "Conformational control in the synthesis of mixed tetraethers of calix[4]arene. Part 2". . p. 16195 - 16204. Retrieved 1997.