N,N-diMethylpyrrolidin-3-aMine dihydrochloride

Base Information

• Chemical Name: N,N-diMethylpyrrolidin-3-aMine dihydrochloride
• CAS No.: 50534-42-4
• Molecular Formula: C₆H₁₄N₂*2ClH
• Molecular Weight: 187.112
• Hs Code.: 2933990090
• Mol file: 50534-42-4.mol

Synonyms:N,N-diMethylpyrrolidin-3-aMine dihydrochloride;3-(DiMethylaMino)pyrrolidine 2HCl

Chemical Property of N,N-diMethylpyrrolidin-3-aMine dihydrochloride

Chemical Property:

• PSA: 15.27000
• LogP: 1.84270
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

N,N-Dimethyl-3-pyrrolidinamine dihydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-diMethylpyrrolidin-3-aMine dihydrochloride

There total 3 articles about N,N-diMethylpyrrolidin-3-aMine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

((R)-1-benzylpyrrolidin-3-yl)dimethylamine (69478-77-9,1235437-44-1,713141-64-1) → 3-(R)-(N,N-dimethylamino)pyrrolidine dihydrochloride (50534-42-4,144043-20-9,864448-61-3)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1021/jm00100a028

Reference yield:

((S)-1-Benzyl-pyrrolidin-3-yl)-dimethyl-amine (69478-77-9,1235437-44-1,713141-64-1) → (S)-(-)-3-dimethylaminopyrrolidine dihydrochloride (50534-42-4,144043-20-9,864448-61-3)

Guidance literature:

With hydrogenchloride; hydrogen; In ethanol; for 1.5h;

DOI:10.1021/jm00100a028

Reference yield:

→ 1-Benzyl-4-(N-methyl-8-azabicyclo[3.2.1]oct-3-yl)-piperazine hydrochloride + 3-(N,N-dimethylamino)pyrrolidine dihydrochloride (50534-42-4,144043-20-9,864448-61-3)

Guidance literature:

upstream raw materials:

((R)-1-benzylpyrrolidin-3-yl)dimethylamine

((S)-1-Benzyl-pyrrolidin-3-yl)-dimethyl-amine

Downstream raw materials:

(+/-)-[1-(2-iodophenyl)pyrrolidin-3-yl]dimethylamine

(+/-)-[1-(2-bromophenyl)pyrrolidin-3-yl]dimethylamine

N-[5-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-2-[(3R)-3-dimethylaminopyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide

N-{5-chloro-(4-pyrazolo[1,5-a]pyridin-3-yl)-pyrimidin-2-yl}-4-[(3R)-3-dimethylaminopyrrolidin-1-yl]-6-methoxybenzene-1,3-diamine