9H-Carbazole, 1-fluoro-

Base Information

• Chemical Name: 9H-Carbazole, 1-fluoro-
• CAS No.: 391-26-4
• Molecular Formula: C12H8FN
• Molecular Weight: 185.201
• Mol file: 391-26-4.mol

Synonyms:9H-Carbazole, 1-fluoro-;1-fluoro-9H-carbazole

Chemical Property of 9H-Carbazole, 1-fluoro-

Chemical Property:

• Melting Point: 164 °C (decomp)
• Boiling Point: 359.2±15.0 °C(Predicted)
• PKA: 16.55±0.30(Predicted)
• PSA: 15.79000
• Density: 1.320±0.06 g/cm3(Predicted)
• LogP: 3.46020

Purity/Quality:

98% ^*data from raw suppliers

1-fluoro-9H-carbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9H-Carbazole, 1-fluoro-

There total 12 articles about 9H-Carbazole, 1-fluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-Fluoroaniline (348-54-9) + 2-bromo-1-chlorobenzene (694-80-4) → 1-fluoro-9H-carbazole (391-26-4)

Guidance literature:

With potassium phosphate; tricyclohexylphosphine; palladium diacetate; In 1-methyl-pyrrolidin-2-one; at 130 ℃; for 18h;

DOI:10.1002/anie.200603833

Reference yield: 73.1%

N-(2-bromophenyl)-2-fluoroaniline (908242-77-3) → 1-fluoro-9H-carbazole (391-26-4)

Guidance literature:

With palladium diacetate; potassium carbonate; In N,N-dimethyl acetamide; at 150 ℃; for 2h;

Reference yield: 67.0%

N-(2-fluorophenyl)-N-phenylamine (328-20-1) → 1-fluoro-9H-carbazole (391-26-4)

Guidance literature:

With palladium diacetate; acetic acid; for 3.16667h; Heating;

upstream raw materials:

8-fluoro-2,3,4,9-tetrahydro-1H-carbazole

chloranil

N-(2-fluorophenyl)-N-phenylamine

2-Fluoroaniline

Downstream raw materials:

fluoro-9-(2-nitrophenyl)-9H-carbazole

1-fluoro-9-(o-tolyl)-9H-carbazole