328-20-1

Basic information

• Product Name: 2-FLUORODIPHENYLAMINE
• Synonyms: 2-FLUORODIPHENYLAMINE;2-Fluorodiphenylamine97%
• CAS NO: 328-20-1
• Molecular Formula: C₁₂H₁₀FN
• Molecular Weight: 187.21
• Mol File: 328-20-1.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 147-148/15mm
• Flash Point: 117.6°C
• Appearance: /
• Density: 1.172g/cm³
• Vapor Pressure: 0.00668mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: 2-FLUORODIPHENYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORODIPHENYLAMINE(328-20-1)
• EPA Substance Registry System: 2-FLUORODIPHENYLAMINE(328-20-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 328-20-1(Hazardous Substances Data)

Usage

General Description

2-Fluorodiphenylamine is a chemical compound with the molecular formula C12H10FN. It is a pale yellow solid at room temperature and is insoluble in water. 2-FLUORODIPHENYLAMINE is mainly used as an intermediate in the production of dyes, pharmaceuticals, and other organic chemicals. It is also used as a stabilizer in the manufacture of plastics and rubbers. However, 2-fluorodiphenylamine is considered to be hazardous to human health and can cause skin and eye irritation upon contact. It is important to handle this chemical with proper safety precautions and to dispose of it in a responsible manner to prevent harm to the environment.

InChI:InChI=1/C12H10FN/c13-11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H

Upstream product

• 462-06-6 fluorobenzene 
• 622-37-7 Phenyl azide 
• 71-43-2 benzene 
• 348-52-7 1-Fluoro-2-iodobenzene 
• 62-53-3 aniline 
• 591-50-4 iodobenzene 
• 348-54-9 2-Fluoroaniline 
• 98-80-6 phenylboronic acid 
• 399-31-5 N-(2-fluorophenyl)acetamide 
• 1072-85-1 o-fluorobromobenzene 
• 1993-03-9 o-fluorophenylboronic acid 
• 586-96-9 Nitrosobenzene 
• 108-90-7 chlorobenzene 
• 32090-98-5 N-phenyl-2-fluoroacetanilide 

Downstream Products

• 129574-36-3 N-(2-fluorophenyl)-4-hydroxy-3-methyl-2(1H)-quinolone 
• 951117-47-8 [PN]H 
• 3665-72-3 5,10-diphenyl-5,10-dihydrophenazine 
• 1638490-78-4 1-(2-fluorophenyl)-4-phenylquinolin-2(1H)-one 
• 129574-30-7 4-Chloro-1-(2-fluoro-phenyl)-3-methyl-1H-quinolin-2-one 
• 129574-30-7 4-Chloro-1-(2-fluoro-phenyl)-3-methyl-1H-quinolin-2-one 
• 129574-30-7 N-(2-fluorophenyl)-4-chloro-3-methyl-2(1H)-quinolone 
• 391-26-4 1-fluoro-9H-carbazole 
• 386-16-3 N-phenyl-N-2-fluorophenylbenzamide 

Relevant articles and documents

Copper-catalyzed, ceric ammonium nitrate mediated N-arylation of amines

Cu-Catalyzed, ligand- and base-free cross-coupling of aryl boronic acids with primary and secondary amines has been reported. This ‘Chan-Evans-Lam' reaction has revealed that at room temperature, with a catalytic amount of copper(ii) acetate and ceric ammonium nitrate (CAN) as an oxidant, N-arylation can result in an effective C-N bond formation. This air stable, practical, robust protocol enables tolerance towards a variety of functional groups on both boronic acid and amine partners.

Ligand-Free Iron-Catalyzed C-F Amination of Diarylamines: A One-Pot Regioselective Synthesis of Diaryl Dihydrophenazines

A one-pot synthesis of various 5,10-diaryl-5,10-dihydrophenazines (DADHPs) from diarylamines has been achieved by using an iron-catalyzed C-F amination. Homodimerization of magnesium diarylamides, followed by defluorinative intramolecular cyclization (dou

Synthesis of Di(hetero)arylamines from Nitrosoarenes and Boronic Acids: A General, Mild, and Transition-Metal-Free Coupling

The synthesis of di(hetero)arylamines by a transition-metal-free cross-coupling between nitrosoarenes and boronic acids is reported. The procedure is experimentally simple, fast, mild, and scalable and has a wide functional group tolerance, including carbonyls, nitro, halogens, free OH and NH groups. It also permits the synthesis of sterically hindered compounds.