Quinoline-8-carbonyl chloride

Base Information

• Chemical Name: Quinoline-8-carbonyl chloride
• CAS No.: 100517-41-7
• Molecular Formula: C10H6ClNO
• Molecular Weight: 191.617
• DSSTox Substance ID: DTXSID90563371
• Wikidata: Q82447797
• Mol file: 100517-41-7.mol

Synonyms:quinoline-8-carbonyl chloride;100517-41-7;SCHEMBL1164312;DTXSID90563371;JLZCPFISUMNHDT-UHFFFAOYSA-N;AKOS012171840

Chemical Property of Quinoline-8-carbonyl chloride

Chemical Property:

• PSA: 29.96000
• LogP: 2.61380
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 191.0137915
• Heavy Atom Count: 13
• Complexity: 207

Purity/Quality:

99%, ^*data from raw suppliers

Quinoline-8-carbonylchloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)C(=O)Cl)N=CC=C2

Technology Process of Quinoline-8-carbonyl chloride

There total 1 articles about Quinoline-8-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

8-carboxyquinoline (86-59-9) → quinoline-8-carbonyl chloride (100517-41-7)

Guidance literature:

With thionyl chloride; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; for 5h; Reflux;

Reference yield: 65.0%

(2-chloro-4-(methylsulfonyl)-3-((2,2,2-trifluoroethoxy)methyl)phenyl)(5-hydroxy-1,3-Dimethyl-1H-pyrazol-4-yl)methanone + quinoline-8-carbonyl chloride (100517-41-7) → 4- (2-chloro-4-(methylsulfonyl)-3-((2,2,2-trifluoroethoxy)methyl)benzoyl)-1,3-dimethyl-1H-pyrazol-5-yl quinoline-8-carboxylate

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 6h;

Reference yield:

2-aminoacetophenone (551-93-9) + quinoline-8-carbonyl chloride (100517-41-7) → N-(2-acetylphenyl)quinoline-8-carboxamide

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 25 ℃; for 4h;

upstream raw materials:

8-carboxyquinoline

Downstream raw materials:

(1'S)-N-(1'-benzyl-2'-hydroxyethyl)-8-quinolinecarboxamide

(1'S)-N-(1'-phenyl-2'-hydroxyethyl)-8-quinolinecarboxamide

Chinolin-8-carbonsaeureanilid

quinoline-8-carboxylic acid benzylamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 100517-41-7 quinoline-8-carbonyl chloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send