1-(chloroacetyl)-6-methyl-1,2,3,4-tetrahydroquinoline

Base Information

• Chemical Name: 1-(chloroacetyl)-6-methyl-1,2,3,4-tetrahydroquinoline
• CAS No.: 57368-83-9
• Molecular Formula: C12H14ClNO
• Molecular Weight: 223.7
• Hs Code.: 2933499090
• Mol file: 57368-83-9.mol

Synonyms:1-(chloroacetyl)-6-methyl-1,2,3,4-tetrahydroquinoline;UKRORGSYN-BB BBV-065386;1-(chloroacetyl)-6-methyl-1,2,3,4-tetrahydroquinoline(SALTDATA: FREE)

Chemical Property of 1-(chloroacetyl)-6-methyl-1,2,3,4-tetrahydroquinoline

Chemical Property:

• Vapor Pressure: 1.48E-07mmHg at 25°C
• Boiling Point: 428.8°C at 760 mmHg
• Flash Point: 213.1°C
• PSA: 20.31000
• Density: 1.201g/cm³
• LogP: 2.57800

Purity/Quality:

98% ^*data from raw suppliers

1-(chloroacetyl)-6-methyl-1,2,3,4-tetrahydroquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(chloroacetyl)-6-methyl-1,2,3,4-tetrahydroquinoline

There total 2 articles about 1-(chloroacetyl)-6-methyl-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-methyl-1,2,3,4 tetrahydroquinoline (91-61-2) + chloroacetyl chloride (79-04-9) → 1-chloroacetyl-6-methyl-1,2,3,4-tetrahydro-quinoline (57368-83-9)

Guidance literature:

In dichloromethane;

DOI:10.3390/molecules26226907

Reference yield:

→ 1-chloroacetyl-6-methyl-1,2,3,4-tetrahydro-quinoline (57368-83-9)

Guidance literature:

Entspr. Stammverb., Cl-CH2-COCl;

Reference yield:

1-chloroacetyl-6-methyl-1,2,3,4-tetrahydro-quinoline (57368-83-9) + methyl (4-hydroxy-2-methylphenoxy)acetate (317319-10-1) → C22H25NO5

Guidance literature:

With potassium carbonate; for 12h;

DOI:10.3390/molecules26226907

upstream raw materials:

6-methyl-1,2,3,4 tetrahydroquinoline

chloroacetyl chloride

Refernces