2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE

Base Information

• Chemical Name: 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE
• CAS No.: 86813-46-9
• Molecular Formula: C11H14ClN3O3
• Molecular Weight: 0
• Mol file: 86813-46-9.mol

Synonyms:2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE

Chemical Property of 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE

Chemical Property:

• PSA: 78.16000
• LogP: 2.53590

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE

There total 4 articles about 2-NITRO-5-(1-PIPERAZINYL)BENZALDEHYDEHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

1-(3-dimethoxymethyl-4-nitro-phenyl)-piperazine → 1-(3-Formyl-4-nitrophenyl)piperazine hydrochloride (86813-46-9)

Guidance literature:

With hydrogenchloride; In isopropyl alcohol; for 1h; Heating;

DOI:10.1248/cpb.49.822

Reference yield: 63.0%

piperazine (110-85-0) + 2-nitro-5-chlorobenzaldehyde dimethyl acetal (13796-06-0) → 1-(3-Formyl-4-nitrophenyl)piperazine hydrochloride (86813-46-9)

Guidance literature:

In N,N-dimethyl-formamide; at 80 ℃; for 4h;

DOI:10.1248/cpb.36.2401

Reference yield:

piperazine (110-85-0) + 2-nitro-5-chlorobenzaldehyde diethyl acetal → 1-(3-Formyl-4-nitrophenyl)piperazine hydrochloride (86813-46-9)

Guidance literature:

With sodium hydroxide; In N-methyl-acetamide;

upstream raw materials:

piperazine

2-nitro-5-chlorobenzaldehyde dimethyl acetal

Downstream raw materials:

1-(3,4-dimethoxybenzoyl)-4-(3-formyl-4-nitrophenyl)piperazine

methyl 2-amino-5-<4-(3,4-dimethoxybenzoyl)-1-piperazinyl>benzoate

4-(4-amino-3-hydroxymethylphenyl)-1-(3,4-dimethoxybenzoyl)piperazine

1-(3,4-dimetoxybenzoyl)-4-<3-(N-methylaminomethyl)-4-nitrophenyl>piperazine