tert-Butyl 5-bromo-3-formyl-1H-indazole-1-carboxylate

Base Information

Chemical Name:tert-Butyl 5-bromo-3-formyl-1H-indazole-1-carboxylate
CAS No.:936132-61-5
Molecular Formula:C13H13BrN2O3
Molecular Weight:325.16
Hs Code.:
Mol file:936132-61-5.mol

Synonyms:tert-Butyl 5-bromo-3-formyl-1H-indazole-1-carboxylate;1-Boc-5-bromo-indazole-3-carbaldehyde

Suppliers and Price of tert-Butyl 5-bromo-3-formyl-1H-indazole-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
1-Boc-5-bromo-indazole-3-carbaldehyde 96%
5g
$ 4880.00

J&W Pharmlab
1-Boc-5-bromo-indazole-3-carbaldehyde 96%
1g
$ 1380.00

J&W Pharmlab
1-Boc-5-bromo-indazole-3-carbaldehyde 96%
500mg
$ 740.00

Crysdot
tert-Butyl5-bromo-3-formyl-1H-indazole-1-carboxylate 95+%
1g
$ 617.00

Chemenu
1-Boc-5-bromo-indazole-3-carbaldehyde 95%
1g
$ 583.00

Alichem
tert-Butyl5-bromo-3-formyl-1H-indazole-1-carboxylate
1g
$ 537.14

Total 6 raw suppliers

Chemical Property of tert-Butyl 5-bromo-3-formyl-1H-indazole-1-carboxylate

Chemical Property:

Boiling Point:437.2±48.0 °C(Predicted)
PKA:-4.94±0.50(Predicted)
PSA：61.19000
Density:1.49±0.1 g/cm3(Predicted)
LogP:3.39450

Purity/Quality:

97% ^*data from raw suppliers

1-Boc-5-bromo-indazole-3-carbaldehyde 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-Butyl 5-bromo-3-formyl-1H-indazole-1-carboxylate

There total 6 articles about tert-Butyl 5-bromo-3-formyl-1H-indazole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 201227-38-5
5-bromo-1H-indazole-3-carboxaldehyde

: 24424-99-5
di-tert-butyl dicarbonate

: 936132-61-5
5-bromo-3-formyl-indazole-1-carboxylic acid tert-butyl ester

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 13h;
DOI:10.1016/j.tetlet.2007.02.042

Reference yield:

: 936132-60-4
5-bromo-N-methoxy-N-methyl-1H-indazole-3-carboxamide

: 936132-61-5
5-bromo-3-formyl-indazole-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 10 percent / LiAlH₄ / tetrahydrofuran / 13 h / -15 - 20 °C

2: 94 percent / triethylamine; dimethylaminopyridine / CH₂Cl₂ / 13 h / 0 - 20 °C

With dmap; lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tetlet.2007.02.042

Reference yield:

: 1077-94-7
5-bromobenzopyrazole-3-carboxylic acid

: 936132-61-5
5-bromo-3-formyl-indazole-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / pyridine; EDC / tetrahydrofuran / 13.5 h / 0 - 20 °C

2: 10 percent / LiAlH₄ / tetrahydrofuran / 13 h / -15 - 20 °C

3: 94 percent / triethylamine; dimethylaminopyridine / CH₂Cl₂ / 13 h / 0 - 20 °C

With pyridine; dmap; lithium aluminium tetrahydride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tetlet.2007.02.042