(S)-4-[[2-[(4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-4-oxobutyric acid

Base Information

Chemical Name:(S)-4-[[2-[(4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-4-oxobutyric acid
CAS No.:2440-62-2
Molecular Formula:C19H19 N3 O6
Molecular Weight:385.376
Hs Code.:
European Community (EC) Number:219-472-6
DSSTox Substance ID:DTXSID70947271
Mol file:2440-62-2.mol

Synonyms:N-succinyl-L-phenylalanine p-nitroanilide;succinyl-L-phenylalanine p-nitroanilide;Suphepa

Suppliers and Price of (S)-4-[[2-[(4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-4-oxobutyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-({1-Benzyl-2-[(4-nitrophenyl)amino]-2-oxoethyl}amino)-4-oxobutanoicAcid
100mg
$ 60.00

TRC
4-({1-Benzyl-2-[(4-nitrophenyl)amino]-2-oxoethyl}amino)-4-oxobutanoicAcid
500mg
$ 90.00

Sigma-Aldrich
N-Succinyl-L-phenylalanine-p-nitroanilide protease substrate
5g
$ 306.00

Sigma-Aldrich
N-Succinyl-L-phenylalanine-p-nitroanilide protease substrate
1g
$ 79.60

Matrix Scientific
4-({1-Benzyl-2-[(4-nitrophenyl)amino]-2-oxoethyl}amino)-4-oxobutanoic acid
1g
$ 120.00

Matrix Scientific
4-({1-Benzyl-2-[(4-nitrophenyl)amino]-2-oxoethyl}amino)-4-oxobutanoic acid
0.500g
$ 100.00

Matrix Scientific
4-({1-Benzyl-2-[(4-nitrophenyl)amino]-2-oxoethyl}amino)-4-oxobutanoic acid
5g
$ 380.00

Crysdot
(S)-4-((1-((4-Nitrophenyl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoicacid 97%
10g
$ 328.00

American Custom Chemicals Corporation
N-SUCCINYL-L-PHENYLALANINE-P-NITROANILIDE 95.00%
1G
$ 210.00

American Custom Chemicals Corporation
N-SUCCINYL-L-PHENYLALANINE-P-NITROANILIDE 95.00%
5G
$ 1027.80

Total 23 raw suppliers

Chemical Property of (S)-4-[[2-[(4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-4-oxobutyric acid

Chemical Property:

Vapor Pressure:6.81E-25mmHg at 25°C
Boiling Point:769.3°C at 760 mmHg
PKA:4.68±0.10(Predicted)
Flash Point:419.1°C
PSA：141.32000
Density:1.383g/cm³
LogP:3.11270
Storage Temp.:−20°C
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:8
Exact Mass:385.12738533
Heavy Atom Count:28
Complexity:563

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-({1-Benzyl-2-[(4-nitrophenyl)amino]-2-oxoethyl}amino)-4-oxobutanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CCC(=O)O
Uses N-Succinyl-L-phenylalanine-p-nitroanilide has been used as a substrate for the hydrolytic activity of chymotrypsin and molar absorptive experiments. It has also been used for monitoring in vitro α-chymotrypsin inhibition assay.

Technology Process of (S)-4-[[2-[(4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-4-oxobutyric acid

There total 6 articles about (S)-4-[[2-[(4-nitrophenyl)amino]-2-oxo-1-(phenylmethyl)ethyl]amino]-4-oxobutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 108-30-5
succinic acid anhydride

: 2360-97-6,14235-17-7,14235-18-8,97471-44-8
L-phenylalanine-p-nitroanilide

: 2440-62-2
N-(3-carboxypropionyl)-L-phenylalanine p-nitroanilide

Guidance literature:: With triethylamine; In pyridine; at 20 ℃; for 2h;
DOI:10.3390/molecules26020482

Reference yield: 71.0%

: 108-30-5
succinic acid anhydride

: 78106-64-6
H-Phe-pNA*HBr

: 2440-62-2
N-(3-carboxypropionyl)-L-phenylalanine p-nitroanilide

Guidance literature:: With triethylamine; In pyridine; for 1h;
DOI:10.1248/cpb.36.4794

Reference yield:

: 14235-15-5,14235-16-6,19647-71-3
benzyl (S)-(1-((4-nitrophenyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

: 2440-62-2
N-(3-carboxypropionyl)-L-phenylalanine p-nitroanilide

Guidance literature:: Multi-step reaction with 2 steps

1: HBr / acetic acid

With hydrogen bromide; In acetic acid; 1: Hydrolysis / 2: Acylation;