2-Methoxyquinoline-6-boronic acid, pinacol ester

Base Information

• Chemical Name: 2-Methoxyquinoline-6-boronic acid, pinacol ester
• CAS No.: 1201644-36-1
• Molecular Formula: C16H22BNO4
• Molecular Weight: 303.16118
• Hs Code.: 2933499090
• Mol file: 1201644-36-1.mol

Synonyms:2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline

Chemical Property of 2-Methoxyquinoline-6-boronic acid, pinacol ester

Chemical Property:

• Boiling Point: 404.1±25.0 °C(Predicted)
• PKA: 3.09±0.43(Predicted)
• PSA: 40.58000
• Density: 1.12±0.1 g/cm3(Predicted)
• LogP: 2.54260

Purity/Quality:

98%min ^*data from raw suppliers

4-Methyl-3-nitroquinoline-6-boronicAcidPinacolEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methoxyquinoline-6-boronic acid, pinacol ester

There total 1 articles about 2-Methoxyquinoline-6-boronic acid, pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-6-bromoquinoline (99455-05-7) + bis(pinacol)diborane (73183-34-3) → 2-methoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline (1201644-36-1)

Guidance literature:

With sodium acetate; N,N-dimethyl-formamide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; at 90 ℃; for 24h;

upstream raw materials:

2-methoxy-6-bromoquinoline

bis(pinacol)diborane

Refernces

• 1、 -. "NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS". Page/Page column 43. . Retrieved 2010/04/25.
• 2、 -. "NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL ANTI-DIABETIC AGENTS". Page/Page column 88-89. . Retrieved 2010/05/14.